…and D21, without adjuvant. Antibody (magnitude and affinity) and cellular responses were assessed post-prime (PP) and post-boost (PB) using Luminex and FACS, respectively. GC/Tfh reactions in draining lymph nodes (dLN)…
Background The immune checkpoint marker programmed cell death protein 1 (PD-1) is commonly expressed on memory T cells and enriched in latently HIV-infected CD4+ T cells, including T follicular helper…
…the stimulation that triggered them by inhibiting the JAK-STAT signaling pathway. SOCS proteins, in particular SOCS3, have also been described as having a central role in metabolic syndrome, diabetes and…
…SIV. Methods: Methods: Sixteen macaques (8 females, 8 males) were immunized (1 dose: 50ng p27=3×10∧11 RNA copies, atraumatic, needleless) at week and monitored over time for specific immune responses in…
…has shifted to predominantly men having sex with men in rural settings where access to PrEP can be an issue, in addition to cost and the need for adherence. As…
HIV-1 can be detected in the brain/CNS, and more conveniently in cerebral spinal fluid (CSF), at all times after infection. Its presence reflects a number of processes ranging from the…
Share Your Thoughts Please join us in remembering the extraordinary life of Dr James G. Hakim by leaving your message of condolence and sharing your stories, memories, and photos. In…
Tuberculosis (TB) accounts for a large burden of morbidity and mortality among persons living with HIV (PLWH). Conventional methods of TB diagnosis, including smear microscopy and Xpert MTB/RIF have lower…
…medication adherence. Eligible participants included English-speaking HIV-positive youth aged 15 to 24, who had personal cell phones with text-messaging capability whom received their HIV medical care at one of three…
…AIDS progression, and confirmed or probable TB by week 48 between arms. Kaplan-Meier method was used to estimate the endpoint probabilities, which were compared with the z-test. We screened 1368…