Background: Doxycycline post-exposure prophylaxis (doxy-PEP) is highly effective in reducing N. gonorrhoeae (GC), C. trachomatis (CT), and syphilis among men who have sex with men (MSM) and transgender women (TGW)….
…NYC SHC. We extracted medical record data from PEP initiation visits during 9/2016-12/2017 with: TDF/FTC/DTV regimen, a baseline metabolic panel, and no HIV medication dispensed in the prior three months…
…doxyPEP doses required to observe a measurable reduction in bSTI incidence, and (iii) to explore the contexts in which its use may be most appropriately targeted. Methods This retrospective analysis…
…with men (MSM) and transgender women (TGW) with a history of sexually transmitted infections (STIs) or multiple sex partners. Doxy-PEP’s effect on population-level incidence of STIs is unknown. Methods: To…
…of GC/CT screening and empiric therapy (Antimicrobial Stewardship) without doxy PEP, Current Practice with doxyPEP, and Antimicrobial Stewardship with doxyPEP. For doxyPEP models, we assumed 30% doxyPEP use among MSM…
…peptides in cytosolic extracts from LRA-treated primary CD4 T cells yielded altered degradation patterns with 4-8 sites significantly changed in a 35-mer and 2-4 in a 24-mer depending on the…
…living in PEPFAR funded and non-PEPFAR countries from 1998 to 2013. Results: We analyzed 252,251 men and 591,714 women using 54 surveys in 14 PEPFAR funded and 8 non-PEPFAR funded…
…and bSTI prevalence were assessed using generalized estimating equations. Results A total of 338 men who have sex with men were included, with a median age of 35 (IQR 30-41)…
…to our Emergency Department (ED) asking for nPEP. Methods: Retrospective Monocentric Observational study including all individuals who consecutively accessed our ED asking for nPEP between January 2011 and July 2023….
Background HIV pre-exposure prophylaxis (PrEP) and doxycycline post-exposure prophylaxis (Doxy-PEP) are increasingly adopted by gay and bisexual men worldwide, but real-world evidence on their population impact remains limited, particularly in…