…responses were enhanced by treatment with HODHBt in combination with IL-15, relative to medium only as follows: (mean/mean) Gag – 6.8-fold (p=0.005), Pol – 6.8-fold (p=0.005), Nef – 12.8-fold (p…
…(mAbs) were isolated from a subtype B infected donor using two parallel Methods: high-throughput B-cell culture followed by microneutralization assays, and fluorescently labeled MPER peptide to capture antigen-specific B cells…
…However, some studies have suggested that HIV-infection might confer some level of intrinsic resistance to CTL-mediated lysis through various mechanisms such as the upregulation of anti-apoptotic factors. Here, we show…
Background: The pandemic response measures have had significant global economic and health impacts with transient reductions in HIV clinic attendance and self-reported anti-retroviral therapy (ART) adherence reported in prior studies….
…AEHI, either with a study-provided integrase inhibitor-based regimen or another prescribed regimen. Fiebig stage at ART initiation was retroactively assigned by centralized testing and categorized per protocol as Group 1…
…endogenous compounds that reactivate latent HIV-1 proviruses, we screened a human hemofiltrate-derived peptide library containing essentially all the peptides and small proteins circulating in blood. To this purpose, we used J-Lat…
…and PEPFAR work plans, meeting notes, reports, and analyzed MOH IPT uptake and treatment outcome data from January 2014 to December 2016 in MS Excel®. Treatment outcomes were defined as:…
…PrEP uptake. Using data from routine behavioral surveillance among men who have sex with men (MSM), we examined recent trends and associations with PrEP use. Data were derived from annual…
…in the sera of individuals. The majority of antibody derived peptides will be identical and shared between many different antibodies. Here, current strategies for identifying antibody specific peptides are described….
…the presence or absence of anti(a)-CD3/anti(a)-CD28 beads, vorinostat (SAHA), panobinostat (PNB), or romidepsin (RMD). Dose-ranging studies were performed and, after treatment with a standardized panel of death peptides, BH3 profiles…