Incretins (Glucagon like peptide-1 [GLP-1] and glucose-dependent insulinotropic peptide [GIP]) regulate glucose homeostasis in HIV-uninfected individuals. Inflammation has been implicated as a cause for insulin resistance (IR) among PLWH. Little…
…(MNC) from rectal biopsy specimens were collected from 30 men who have sex with men (MSM) with a potential sexual exposure. All of them were selected from two different PEP…
Background Doxycycline post-exposure prophylaxis (DoxyPEP) prevents bacterial STIs in trials, but real-world effectiveness and safety signals remain uncertain. Methods We reviewed people presenting to a community sexual health clinic in…
…MSM were randomized and 545 were analyzed. Median age: 40 years (IQR 34-48), median of 10 sexual partners in past 3 months. Median follow-up: 14 months. There was no interaction…
…disruptions and ensure treatment access and outcomes. Methods We sourced 2024 conflict data from the Armed Conflict Location and Event Data Project (ACLED) for 24 sub-Saharan African countries. We extracted…
Presentation: Increased rates of bacterial sexually transmitted infections (STIs) are reported among men who have sex with men (MSM), particularly among those using HIV pre-exposure prophylaxis (PrEP). Interventions to reduce…
…that inhibited infection with genuine SARS-CoV-2. Our work demonstrates the feasibility of inhibiting SARS-CoV-2 with peptide-based inhibitors. These findings will allow for the successful development of engineered peptides and peptidomimetic-based…
…of PLHIV in DRC. We aimed to evaluate the proportion and characteristics of PLHIV who were lost from treatment and died in DRC PEPFAR programs. We conducted an analysis using…
…visits. Logistic regression with Generalized Estimating Equations (GEE), to account for repeated measures, was used to assess the associations between DoxyPEP use and HR/R/DS rates. GEE model with log-transformed MICs…
…with 28 days of PEP medication before an exposure occurs, along with instructions on when to initiate medications and how to follow up with care. We present long-term follow-up of…