…(ART+DTG+MVC+Au), G5) partially intensified ART (DTG)+DCv, G6) partially intensified ART (DTG)+NA+Auranofin+DCv. Au was used for the first 24 weeks. DC was pulsed with autologous Gag256-367 peptides (nanomers, 3-6 peptides each…
…peptide. At day five we measured activation (Ki67, GrzB) and differentiation of tetramer positive cells (Id2 levels and CCR7,CD27,CD45RA). Cytolytic activity was measured by a cell-based assay that measures the…
…between Tat and amyloid beta (Aβ) peptide. Tat was measured by ELISA in CSF of patients with HIV infection on antiretroviral therapy. Evaluations included neurocognitive tests, CSF cytokines, Aβ peptide,…
…conserved virus-derived peptide antigens. Methods We constructed plasmids encoding single chain HLA-A*0201 MHC molecules tethered to viral-derived peptides, either alone (modless) or in combination with an agonist αCD28 scFv, to…
…now is to combine knowledge of the BG505 SOSIP.664 trimer structure with a better understanding of the immunology of bNAb development during infection, to guide improvements to Env trimer-based immunogens….
…was efavirenz/lamivudine/tenofovir disoproxl fumarate. The median duration of this regimen was 2.25 (IQR 0.94-3.88) years. The initial regimen was switched or stopped for 1207 (45%) participants for reasons including change…
…for survey year, race, insurance, income, number of casual partners, HIV tests in the last year, and having heard of and used post-exposure prophylaxis (PEP). Among 460 participants, 53 (12%)…
…and specificity for the Cepheid POC assay in the first week of life despite low median infant HIV RNA and extensive PEP. The Cepheid POC testing platform may be a…
…Fund, PEPFAR, and the Bill and Melinda Gates Foundation (BMGF) announced efforts to ensure two million people have equitable access to affordable Lenacapavir for three years. Recent termination of several PEPFAR…
…an academic medical center and an SEP to deliver low barrier healthcare to people who use drugs (PWUD) onsite at an SEP. A Montefiore Medical Center clinic was opened…