…of programmatic efforts across 21 PEPFAR-supported countries in sub-Saharan Africa. Methods Historical aggregate PEPFAR program data from 2017 to 2024 were analyzed to identify key factors associated with VLS improvement….
Although the CDC estimates that >400,000 U.S. men who have sex with men (MSM) are PrEP candidates, uptake initially was slow. Monitoring recent trends is important to ensure wider access…
…3-month unhealthy alcohol use [Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) score (≥3 women; ≥4 men)] and HIV risk (self-perceived or reported sexual risk behavior) and were referred to pre- or post-exposure prophylaxis…
…prevention coverage. Methods: We conducted an individually randomized trial (SEARCH; NCT04810650) among women (≥15 years) with current or anticipated risk of HIV infection seen at ANC clinics in rural Kenya…
…of programmatic efforts across 21 PEPFAR-supported countries in sub-Saharan Africa. Methods Historical aggregate PEPFAR program data from 2017 to 2024 were analyzed to identify key factors associated with VLS improvement….
…is aimed to relieve exhausted T-cells and to stimulate recall memory T-cells. We have developed an antigen-presenting cell (APC)-targeting approach allowing the delivery of specific antigens through a mAb targeting…
…INI1-Rpt1/IN-(C-terminal domain) CTD complex to generate hydrocarbon stapled peptides derived from interface α1 helix of INI1-Rpt1. These peptides were tested for their effect on IN-INI1, INI-RNA interactions using Alpha Assay…
…performed by chi-square test. Results: Only IL-8 levels were sufficient to permit quantitative correlation (Median = 0.72 log10, IQR = 0.18-1.38 log10). Among penile bacteria significantly reduced by MC in…
…mechanism is lacking. Methods: We characterized HIV integration sites and used digital PCR assays to measure total, intact, and provirus-specific HIV DNA in an elite controller (EC) before and after…
…Phenotypic analysis indicated antigen-specific memory was associated with increased NKG2C and CD57 expression. Accordingly, NKG2C receptor blockade and pulsing with single HIV-derived peptides that bind HLA-E indicated memory NK cell responses…