…median of 258(IQR 254-285) days ago; those vaccinated with one dose a median of 339 days ago(IQR 288-349) and those who received two doses 126(IQR 72-169) days ago. The median…
…(VL) near delivery; infant post-exposure prophylaxis (PEP); no breastfeeding. Despite fulfilling these criteria, we present two cases of vertical transmission from one UK centre and review the literature. Methods: Retrospective…
…in countries with active PEPFAR support (86%) at the beginning of 2025. Substantial proportions reported disruptions in HIV-related service delivery (47%), medication availability (28%), laboratory services (34%) and other clinic…
Background: At 54.8 cases per 100,000 women, Uganda is one of the highest cervical cancer (CxCa) burdened countries in the world. Women living with HIV (WLHIV) are 6 times greater…
…from 4004 HIV-1 strains. CXCR4-targeting cyclic-peptide (CycPep) was conjugated with PEG-lipid to make DSPE-PEG-CycPep and LNP was formulated by microfluidic mixing. The specificity of the CXCR4 receptor was shown by…
…exhaustion. In contrast, chronic cytomegalovirus (CMV) infection induces a unique CTL response termed memory inflation characterized by continued expansion following priming, maintained “effector‐memory” phenotype, and sustained functionality. As T cell…
…of immunosuppression (median CD4:931, IQR:394-892, CD8:515, IQR:393-892). Plasma and PBMC samples from past-infection (PI) cohort (n=9, median age= 42, IQR=36-47) and vaccination (Vax) cohort (n=8, median age =41, IQR=41-53) were…
…IL-2 production in response to S-WT, S Delta variant and N protein overlapping peptides by intracellular cytokine staining (ICS). Splenocyte cytokine secretion upon stimulation with S-WT/N peptides was also assessed…
…mapping methods. Here we developed and tested a high-throughput, comprehensive approach to map the epitopes of recently identified HIV-specific monoclonal antibodies (mAbs) that mediate ADCC. We applied a phage display…
…IAS-USA efforts. Read article IN MEMORIAM: Dr James G. Hakim It is with deep sadness that we learned of the death of Dr James G. Hakim. An acclaimed researcher and…