The COVID-19 pandemic has interrupted the implementation of many HIV prevention programs supported by the US President’s Emergency Plan for AIDS Relief (PEPFAR), especially in sub-Saharan Africa. We evaluated the…
…study, 26 men had high grade disease at study entry a mean 1 year prior, of which 6 experienced spontaneous regression by the time these assays were performed. Five (83%)…
…HIV-infected patients were treated with GS-9620 in the presence or absence of HIV peptides. To assess the role of type I interferons in the effects mediated by GS-9620, an antibody…
…gamma-interferon ELISPOT with HIV full genome 15-mer overlapping peptides, proliferation (Cell Trace Violet) and Activation Induced Marker (AIM) assays (CD25, OX40, 41BB, CD69), the latter two using pooled peptides (Gag,…
Prior to the President’s Emergency Plan for AIDS Relief (PEPFAR) Program, patients initiating antiretroviral treatment (ART) in resource-limited settings frequently had very advanced immunodeficiency. In this study, we examined CD4…
…less defined. Methods We studied 5 PICs (4 males, 1 female) with prolonged viral suppression (median 6 years, IQR 3.6-6.4) after analytical treatment interruption (ATI) following broadly neutralizing antibody therapy….
…metagenomes were analyzed for taxonomy (mOTUs3) and function (eggNOG-mapper). Inactivated fecal bacterial communities (FBC) and sterile filtrates (SF) were prepared. CP’s PBMCs were primed with SF or FBC, stimulated with…
…The breast cancer cell line T-47D was used as control and all experiments were performed in hormone-free media. Results: In contrast to T-47D breast cancer cells, in CD4+ T cells…
The last 10 years have been transformational for laboratory medicine in Africa thanks to increase in global health funding, especially from the world bank, PEPFAR, the Global fund–etc. Laboratory networks…
…summed the enrichments of the corresponding peptides for each strain. Binomial logistic regression of enrichment and maternal viral load was used to determine whether regional responses were associated with HIV…