…that a single low oral dose given within 24 hours of HIV exposure may provide effective PEP. These results support the potential utility of ISL as a simplified PEP agent….
…women), 55/359 (15.3%) chose oral PrEP (29 women), and 28/359 (7.8%) chose PEP (14 women). None chose the dapivarine ring. At enrolment, 88/315 (27.9%) had an STI (gonorrhoea or chlamydia)….
…cell-free virions, leading to virus core release. We seek to understand the mechanism of this cell-free virolysis. We hypothesize that the PT-SH hijacks the viral fusion mechanism prior to cell…
Background: Although HIV pre-exposure prophylaxis (PrEP) use has been shown to decrease HIVincidence among men who have sex with men (MSM), uptake has not been widespread, and the demographics and…
…were observed. PEP E/C/F/TAF was well tolerated and demonstrated good completion rates. Self-reported and drug levels indicated good adherence, confirming that E/C/F/TAF could be a regimen of choice for PEP….
…study evaluated CD4 testing coverage and AHD prevalence at U.S. Agency for International Development (USAID) sites supported by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). Methods The PEPFAR…
…viral load and onward HIV transmission. To better understand continuity of treatment, we analyzed treatment interruption patterns among children, adolescents, and young adults in USAID-supported PEPFAR countries. Methods: Routinely collected…
…household contacts (HHC) of index patients (IP) with COVID-19. Methods SCORPIO-PEP was a double-blind, placebo-controlled trial in HHC of IP with laboratory-confirmed COVID-19 conducted in the US, Japan, and other…
…NRTIs + EFV regimen was significantly associated with premature discontinuation of occupational PEP. This regimen should not be further used for HIV prophylaxis following occupational exposure in the resource-limited settings….
…NRTIs + EFV regimen was significantly associated with premature discontinuation of occupational PEP. This regimen should not be further used for HIV prophylaxis following occupational exposure in the resource-limited settings….