…unknown. The CHAPS trial addressed these gaps of knowledge and pre-clinically assessed post-exposure prophylaxis (PEP) in foreskin. Methods: Phase 2 open-label, randomised controlled trial in Uganda and South Africa. 144…
…additionally offered post-exposure prophylaxis (PEP) and sexually transmitted infection (STI) testing. Methods: We piloted the modified delivery model in 12 private pharmacies in Kisumu and Kiambu Counties. Pharmacy providers were…
…(SoC) among men and women at risk for HIV in rural Uganda and Kenya. Methods: Participants were recruited from three randomized studies of the SEARCH dynamic choice HIV prevention (DCP)…
…capabilities of SARS-CoV-2-specific CD4+ and CD8+T cells were measured by FACS after stimulation with a pool of overlapping SARS-CoV-2 viral peptides (M, N and S). Pattern variations associated with viral-specific…
…prophylaxis (PEP) was efficacious at preventing STIs among cisgender men who have sex with men and transgender women, but no trials among cisgender women have been done. Methods: We conducted…
…strategy.Data is collected on PNS, contacts of index cases and HIV indicators as Monitoring, Evaluation and Reporting (MER) data.These data measures progress towards HIV epidemic control by reaching the first UNAIDS…
…analysed for expression of viral peptide-HLA complexes by total internal reflection microscopy (TIRF; single molecule epitope counting). Results: HIV Gag peptide-HLA complexes could be identified on peptide pulsed cells using…
…may be effective in immune clearance. Methods Using the Immune Epitope Database, we created a panel of 46 peptides derived from proteins produced early in poxvirus infection also present in…
Background: Obstructive lung disease (OLD) is increasingly common among persons with HIV (PWH). The role of proteases in HIV associated OLD is unknown. Methods: We performed mass spectrometry (MS) analysis…
…imaging of the axillary lymph nodes may provide a method to non-invasively measure reservoirs of viral persistence in HIV and assess response to different antiretroviral therapies or anti-inflammatory interventions. …