…VL350) underwent leukapheresis, lymph node biopsy and rectal biopsy. Following cell isolation, flow-based sorting was used to isolate naive (Nv), central- (CM), transitional- (TM) and effector- (EM) memory populations. Cellular…
…change in risk (1), or travel outside the community (2). Conclusions Among women offered prevention options in a Dynamic Choice model that included oral PrEP, PEP, and CAB LA, adding…
…peptides showed enrichment in the highest number of participants (n=3), while most other peptides enriched in only one participant. Moreover, unlike other top peptides, Sox5 has CNS-specific functions involving neuronal…
…is very limited evidence documenting efficacy in this setting. We report the successful use of combination PEP following transfusion of HIV infected blood from a viremic donor source. Methodology: A…
…care. Primary outcome over 48 weeks was biomedical covered time (proportion of follow-up covered by PrEP/PEP), assessed via self-report; secondary outcomes included coverage during periods of retrospectively self-assessed HIV risk….
…energy mediating porous silicon nanodisks, functionalized with customized antibodies highly specific to Mtb antigen peptides, and high-throughput mass spectrometry (NanoDisk-MS) for dual enhancement of sensitivity and specificity. Serum samples are…
…define the window of PEP activity by applying inserts 8 or 24 hours after SHIV exposure. Methods: Cycling pigtailed macaques were challenged with low-dose SHIV162p3 and dosed 8 or 24h…
…in the dPEP (n=224) and SOC groups (n=225). Overall, participants had a median age of 24 years, reported a median of 2 sexual partners, and 36.7% engaged in transactional sex….
Improved methods are urgently needed for pediatric tuberculosis (TB) diagnosis. We evaluated the performance of a blood-based assay (NanoDisk-MS), which utilizes immunoenrichment and mass spectrometry to quantify a TB-specific CFP-10 peptide,…