…three PICs with suppressed viral load for >6.5 years (ID107), >7.5 years (ID9254) and 2.5 years (ID142) following HIV-1 broadly neutralising antibody administration. Methods The intact/inducible proviral reservoir was quantified…
…visceral adiposity, blood pressure, glucose metabolism, and lipids in PWH and lipohypertrophy. The current analysis investigates effects of semaglutide on measures of subclinical cardiovascular health. Methods Virologically-suppressed PWH without known…
Background: Increasing evidence suggest that HIV can be controlled by Natural Killer cells (NK cells), via multiple mechanisms including antibody dependent cellular cytotoxicity (ADCC). In the RV144 vaccine trial, that…
…NK cell ADCC responses were determined against antibody coated Raji cells. The metabolic profile was assessed by a Seahorse technology. Soluble markers were measured using multiplexed assays.The Mann–Whitney U, Wilcoxon-test,…
…Kaplan-Meier estimators and log-rank tests. LTF after ART initiation was defined as no visit >6 months; deaths were ascertained from medical records. The combined endpoint was used as deaths are…
…8%. In this context, the study compares the effectiveness of CRO 1g IM monotherapy versus combination in eradicating NGIs. Methods All NGIs diagnosed at our clinic between January 2022 and…
…by leukapheresis, separated by Ficoll centrifugation, and treated with GS-9620 (20 and 1000 nM) or vehicle alone for 24 hours. HIV pentamers (Proimmune) composed of five MHC Class I peptide-complexes…
…– 2013, of whom 21895 (36.9%) had documented CD4 results at entry into care. Of these, 73% were women; median age was 32 years (Interquartile range: 26, 39). The median…
Background: The PrePex™ device offers an alternative to conventional surgical methods of male circumcision. Because it does not require injectable anesthesia or the cutting of vital tissue, PrePex™ requires less…
…to evaluate the efficacy of berberine for improving clinical features, insulin resistance, metabolic profile, and inflammatory markers. Methods: A randomized, double-blind, placebo-controlled trial was performed in adults living with HIV…