…and hypertension. Participants underwent a clinical assessment, echocardiography (Echo), and measure of b-type natriuretic peptide (BNP). Echo parameters defined structural abnormalities of the left atrium and left ventricle (LV), increased…
…among adults (1.4 overall) was greater among men (1.8) than women (1.1). Contact testing had the highest yield (8.9%, 2018; 14.3%, 2019) and was the second largest contributor to overall…
…T-cell function in people living with HIV (PLWH) on antiretroviral therapy (ART). Methods: Plasma ACBP and cytokines were quantified by ELISA in 50 PLWH on effective ART (mean duration 14.7…
…Protocol C’. Samples were collected at two weeks (median=18 days), 1-month (median= 32 days), and 3-month (median=91 days) post-HIV-1 infection. Multiparameter flow cytometry was used for phenotypic characterisation. ADCC responses…
…as controls. Cell immunophenotyping was performed by flow cytometry. Cytotoxic activity was determined using NK-specific target cells K562 and HIV-1-infected TZM-bl. Cytokine release was measured after stimulation with HIV-1 peptide…
Background: CMV is associated with persistent inflammation in HIV-infected persons. Here, we studied the effect of HIV expanded myeloid derived suppressor cells (MDSCs) in controlling CMV specific inflammation. Methods: PBMCs…
…HIV testing services in Brazil (6 cities) and Peru (7 cities) from Jan/21-May/22. Inclusion criteria: 18+ years, cisgender men who have sex with men (cis-MSM), transgender women (TGW) and other…
…with low VLT coverage (VLTC)), we analyzed data reported to the Monitoring, Evaluation, and Reporting (MER) System by 17 PEPFAR-supported sub-Saharan African countries in 2019 and 2020. We used ordinal…
…vaccinal effect on HIV-specific T cells, increasing response frequencies and improving functional properties during bNAb-mediated suppression. Here, we evaluated whether such a vaccinal effect occurred in the BEAT2 clinical trial,…
…size and HIV specific immune responses in participants of the Netherlands Cohort Study on Acute HIV Infection (NOVA study), who initiated ART immediately after diagnosis of AHI. Methods: Participants in…