CROI 2026: Late-Breaking Abstract Review
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1218 – Trends in 2016 CDC-Recommended PEP Regimens and Bictegravir for HIV PEP: United States, 2015-2023
…reported the annual number of PEP users, stratified by regimen type, days of supply, and PEP user demographic characteristics. Results During 2015−2023, the annual number of persons prescribed PEP ranged…
SELF-START HOME PEPSE TO REDUCE UPTAKE TIME AND INCREASE PEPSE EFFICACY: RCT
…prevent people accessing PEPSE. We hypothesized that advanced provision of a 5-day PEP starter pack (HOME PEPSE) for men who have sex with men (MSM) to keep at home and…
Uptake and Predictors of PEP Uptake in the SEARCH Dynamic Choice HIV Prevention Trials
…PEP start. In SoC: 28 PEP courses among 20 participants; 8 participants used multiple PEP courses; 2 participants transitioned to PrEP the month after PEP start. Biomedical covered time (%…
163 – High Sustained Effectiveness of Doxycycline PEP for STI Prevention After Clinical Implementation
…use, time (in quarters), and DPEP initiation (pre-post DPEP prescription for the DPEP Users, and pre-post median time for the non-DPEP users). Results Overall, 4,149 clients (2,419 DPEP users and…
Doxycycline PEP: High Uptake and Significant Decline in STIs After Clinical Implementation
…11/30/22. We included PrEP clients with at least one STI test who received DPEP for at least 30 days (DPEP users), or never initiated DPEP (non-DPEP users). The ‘pre-DPEP’ period…
1219 – Impact of Initiation Delay, Duration, and Prior PrEP Usage on FTC/TDF-Containing PEP Efficacy
…clinically to inform PEP recommendations. Methods We employed pharmacokinetics, pharmacodynamics, and viral dynamics models, incorporating individual factors such as self-start PEP and PEP adherence to investigate the impact of initiation…
1358 – Regional Disparities in DoxyPEP Uptake Despite High Awareness Among MSM With HIV in the US
…currently prescribed doxyPEP and 31% remained unaware of doxyPEP. Of the 413 respondents unaware of doxyPEP, 83% were interested in doxyPEP and 80% of those not on doxyPEP stated they…
USE OF HIV PEP BY US COMMERCIALLY INSURED PERSONS INCREASED WITH AVAILABILITY OF PrEP
…of both PEP and PrEP use during 2005-2015. The increase in PEP use might be associated with increased awareness of PEP as a result of PrEP social media and educational…
1038 – Differential Risk Reduction of Gonorrhea and Chlamydia Among DoxyPEP Users Reporting High Adherence
…use: (1) any self-reported current use of DoxyPEP among all Magnet clients and (2) DoxyPEP adherence in the past 3 months, measured as self-report of always using DoxyPEP within 72…