Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.
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1277 Results
Background Incidence of syphilis has increased over the last 20 years. This increase might be followed by a rise in neurosyphilis (NS), especially in the HIV population. Surveillance for NS is heterogeneous and thus the real incidence is not well known. These factors highlight the need for a standardized evaluation process. Therefore, we aim to…
Background Black women in the U.S. are disproportionately impacted by STIs/HIV, largely due to political, social, and structural determinants of health. Despite these glaring disparities, sexual reproductive health (SRH) services continue to be fragmented and challenging to access. This study examines the relationship between family planning service (FPS) use and engagement in STI/HIV testing among…
Background 9-valent HPV vaccine is effective as a prevention tool, rather than therapeutic at cervical site. Insights on viral clearance at anal site is still unknown, especially in the high-risk population of MSM with HIV. Aim of the study is to determine factors associated with the clearance of at least one genotype included in the…
Background Women who engage in sex work (WESW) and their partners have an elevated risk of exposure to sexually transmitted infections (STI) and account for an increasing proportion of new HIV infections globally. In Uganda, HIV prevalence among WESW is over 30%. Oral pre-exposure prophylaxis (PrEP) could substantially reduce HIV incidence among WESW and is…
Background Syndromic management of STIs often limits their detection and targeted treatment. MSW typically display low health-seeking behavior and this,paired with exposure to asymptomatic STIs from partners, exacerbates risks of transmission. MSM, perceiving marginalization within health services, typically limit STI symptom-reporting essential for initiation of treatment algorithms. Diagnostic STI testing and management are therefore critical…
Background The distribution of HIV-1 genetic variants among people living with HIV (PLHIV) is important for the design of vaccines and broadly neutralising antibodies (bNAbs) as well as for the accuracy of tests for diagnosis and viral load. This study aimed to compare the distribution of HIV-1 variants from population-based national surveys in sub-Saharan countries.…
Background There were 1.3 million new HIV acquisitions worldwide in 2023, far over UNAIDS target of <370,000 by 2025. Novel injectable pre-exposure prophylaxis (PrEP), lenacapavir (LEN), has superior efficacy to oral TDF/FTC. Gilead are drafting a voluntary license (VL) for LEN. We analysed the rate of HIV epidemic growth for countries inside and outside of…
Background Intracellular tenofovir diphosphate (TFV-DP) concentrations from F/TDF PrEP in dried blood spots are ~30-50% lower during pregnancy, but data on TFV-DP levels achieved in peripheral blood mononuclear cells (PBMCs), the clinically relevant site for HIV prevention, are limited. We evaluated the effect of pregnancy on TFV-DP levels in PBMCs and birth and infant growth…
Background Clinical decision support (CDS) systems are a promising strategy to improve HIV screening in pediatric settings. We assessed effectiveness of a CDS system to improve HIV screening at well-adolescent visits. Methods In this quasi-experimental pragmatic study, we developed and launched an electronic health record (EHR)-based CDS system across a 31-clinic, northeastern U.S, pediatric primary…
Background Long-acting cabotegravir and rilpivirine (LA-CAB/RPV) is a novel injectable antiretroviral therapy approved for virologically suppressed individuals with HIV-1. Data on the safety, efficacy, and outcomes for individuals receiving LA-CAB/RPV during pregnancy are limited. We evaluated HIV viral suppression, perinatal, and neonatal outcomes in pregnant persons with HIV-1 receiving LA-CAB/RPV. This is the first case…