Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.
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1277 Results
Background Congenital syphilis (CS) is an urgent threat; cases are at their highest rate (102.5/100,000 live births) since 1991. The only treatment (tx) for late latent syphilis (LLS) in pregnancy is 3 doses of benzathine penicillin G (BPGx3), given at 7-day (d) intervals. If intervals exceed 9d, US guidelines recommend restarting the full tx series,…
Background People who inject drugs (PWID) face high morbidity and mortality from addiction and HIV. This abstract reports findings from HPTN 094 on whether 26 weeks of “one stop” integrated health services delivered in a mobile unit, supported by peer navigation, improves use of MOUD, increases viral suppression among people with HIV (PWH), and increases…
Background As ART coverage expands in Africa, a greater proportion of persons remaining with viremia are predicted to be HIV serostatus aware and treatment-experienced, potentially reducing the need for population surveillance and community outreach. However, population-level data on the care status of persons with viremia remains limited in African settings achieving “95-95-95” treatment targets. Methods…
Background Viral suppression estimates are essential for monitoring progress towards the UNAIDS 95-95-95 targets. We sought to generate updated estimates of viral suppression rates in South African adults on antiretroviral treatment (ART) to understand changes in viral suppression following the introduction of dolutegravir and the COVID-19 epidemic. Methods This retrospective cohort study included adults (15 years…
Background Clinic transfers in African countries with high HIV burdens are common, but nationally representative data on clinic switching are scarce, and the relationship between facility switching and HIV care engagement is poorly understood, especially at the population level. Methods We pooled data from six Population-based HIV Impact Assessment (PHIA) surveys (2020-21) in Eswatini, Lesotho,…
Background UNAIDS estimates, derived by fitting mathematical models to national surveillance data, indicate that HIV incidence in sub-Saharan Africa has declined substantially since 2000. We assessed whether the level and age distribution of HIV incidence from mathematical-model derived estimates, which are critical to guide epidemic response strategies, are consistent with empirical HIV incidence observations. Methods…
Background Men’s suboptimal HIV treatment outcomes hinder epidemic control efforts and jeopardize men’s health. Interventions tailored to men’s unique needs are essential, although rarely tested. We tested the effect of person-centered care interventions on ART engagement among men living with HIV but not in care in Malawi. Methods We conducted an individually randomized control trial…
Background The Africa CDC and the WHO declared Mpox a Public Health Emergency of Continental Security and of International Concern respectively. The first Mpox-positive cases in Uganda were reported in July 2024 from Kasese District, Bwera Hospital by the Uganda Virus Research Institute (UVRI) and MRC/UVRI & LSHTM Uganda Research Unit. In light of ongoing Mpox…
Background High blood pressure (≥90mmHg/140mmHg) is associated with ~35% of sub-Saharan Africa deaths. In Mozambique, 3% of hypertensive adults achieve controlled blood pressure (BP). Systems engineering strategies applied at the health facility level, like the Systems Analysis and Improvement Approach (SAIA), have been shown effective in improving quality and continuity of health service delivery in…
Background Long-acting injectable cabotegravir (CAB-LA) is highly effective as PrEP but may delay detection of HIV infection using conventional diagnostics. HIV RNA testing may assist with early detection of HIV infection and prevent the emergence of resistance. We evaluated the performance of HIV RNA screening in the HPTN 084 open-label extension (OLE). Methods HPTN 084…