Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.
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1277 Results
Background 9-valent HPV vaccine is effective as a prevention tool, rather than therapeutic at cervical site. Insights on viral clearance at anal site is still unknown, especially in the high-risk population of MSM with HIV. Aim of the study is to determine factors associated with the clearance of at least one genotype included in the…
Background Women who engage in sex work (WESW) and their partners have an elevated risk of exposure to sexually transmitted infections (STI) and account for an increasing proportion of new HIV infections globally. In Uganda, HIV prevalence among WESW is over 30%. Oral pre-exposure prophylaxis (PrEP) could substantially reduce HIV incidence among WESW and is…
Background Syndromic management of STIs often limits their detection and targeted treatment. MSW typically display low health-seeking behavior and this,paired with exposure to asymptomatic STIs from partners, exacerbates risks of transmission. MSM, perceiving marginalization within health services, typically limit STI symptom-reporting essential for initiation of treatment algorithms. Diagnostic STI testing and management are therefore critical…
Background Doxycycline postexposure prophylaxis (PEP), taken within 72 hours of condomless sexual exposure, did not reduce incident bacterial STIs among cisgender women in the only trial conducted to date; use of doxycycline PEP in that trial was low. Methods We describe 35 breakthrough cases of incident Chlamydia trachomatis among 32 participants assigned to doxycycline PEP…
Background Doxycycline post-exposure prophylaxis (doxy-PEP) offers a cheap and effective method for pharmacologic syphilis and chlamydia prevention among men who have sex with men but is underutilized by populations most in need. While syphilis can be easily treated and prevented, young Black sexually minoritized men (YBSMM) in the United States continue to bear the brunt…
Background People living with HIV (PLWH) and health systems caring for them were hit hard by the COVID-19 epidemic and illicit drug toxicity crisis. These challenges have been further compounded by voluntary and involuntary migration and displacement due to war, political violence, and, for PLWH, stigma and discrimination. These crises have tested the resilience of healthcare…
Background In 2015, the CDC estimated that 1.2 million Americans could benefit from PrEP; however, this may now be outdated, particularly given ambitious CDC HIV elimination goals. Methods Using responses to the most recent suitable NHANES survey (2015/16), including respondent age and sex, number and sex of sexual partners, number of times having sex, condom…
Background The Ending the HIV Epidemic (EHE) program was launched in 2019 with the goal of reducing HIV transmission in the US by 75% by 2025 and 90% by 2030. Men who have sex with men (MSM) are a priority population in this effort. Our objective was to model the impact of improvements across the HIV…
Background Despite scale-up of HIV testing, ART, and pre-exposure prophylaxis (PrEP), there continue to be over 140,000 new HIV infections in South Africa each year. Our objective was to estimate the optimal distribution of resources to HIV testing, ART, and PrEP to reduce HIV transmission in South Africa. Methods We developed an optimization model to…
Background The Centers for Disease Control and Prevention (CDC) recommends routine HIV screening of persons aged 13-64 years and additional testing for those with exposure risk or symptoms. All positive HIV antigen/antibody (Ag/Ab) immunoassay results should be confirmed with HIV antibody differentiation and HIV RNA testing to resolve conflicting results. Understanding the performance and efficiency…