CONFERENCE ON RETROVIRUSES
AND OPPORTUNISTIC INFECTIONS

Boston, Massachusetts
March 8–11, 2020

 

Preliminary Agenda

Sunday, March 8, 2020

8:00 AM - 8:50 AM
  • The Hitchhiker's Guide To NIH Review For HIV/AIDS Research
    Convener: Guido Silvestri, Emory University

    Overview of HIV/AIDS Review at CSR
    Shiv A. Prasad, National Institutes of Health

    The NIH Grant Application Process
    Dimitrios Vatakis, National Institutes of Health

    A New Investigator's Perspective
    Sarah Beth Joseph, University of North Carolina
9:00 AM - 12:25 PM
  • Program Committee Workshop for New Investigators and Trainees
    Conveners: John W. Mellors, University of Pittsburgh, and Serena S. Spudich, Yale University

    Advances in Molecular Virology
    Wesley I. Sundquist, University of Utah

    Advances in HIV Immunology and Vaccines
    Richard A. Koup, National Institutes of Health

    Issues in Maternal, Infant, and Child Health
    Hermione Lyall, Imperial College Healthcare NHS Trust

    Advances in HIV Prevention
    Susan P. Buchbinder, San Francisco Department of Public Health

    Advances in HIV Cure
    Nicolas Chomont, Université de Montréal
12:25 PM - 1:40 PM

Lunch and Martin Delaney Presentation

  • Martin Delaney Presentation: Shifting From Acute to Chronic: Aging, Longevity, and Lived Experience
    Panelists: Jim Pickett, AIDS Foundation of Chicago, Martha Tholanah, Just Associates, Gabriel Maldonado, TruEvolution, and Celeste Watkins-Hayes, Northwestern University
2:00 PM - 4:00 PM

Concurrent Preconference Workshops


  • Frontiers in Laboratory Science
    Conveners: Galit Alter, Ragon Institute of MGH, MIT and Harvard, and Frank Kirchhoff, Ulm University Medical Center

    Shaping Vaccines With DNA Origami
    Mark Bathe, Massachusetts Institute of Technology

    Concepts In Reservoir Measurements
    Janet M. Siliciano, Johns Hopkins University

    Charting Genome-Wide Integration
    Mary F. Kearney, National Cancer Institute

    Single-Cell Epigenetics: Coloring Immune Cells With a Rich Pallette of Histone Marks
    Alex J. Kuo, Stanford University
     
  • Clinical Trial Design and Analysis
    Conveners: Susan P. Buchbinder, San Francisco Department of Public Health, and Richard E. Chaisson, Johns Hopkins University

    Putting Analysis Into Analytical Treatment Interruptions
    Lu Zheng, Harvard T. H. Chan School of Public Health

    Advancing From Phase II to Phase III: Navigating the Land of Expectations
    Patrick PJ Phillips, University of California San Francisco

    Noninferiority Complex
    Jeffrey Scott Murray, Food and Drug Administration

    Inclusion of Diverse Populations In Trials
    Mark Harrington, Treatment Action Group
     
  • Interactive Case-Based Workshop: What's Eating Your Liver
    Conveners: Oluwaseun Falade-Nwulia, Johns Hopkins University, and Nadine Kronfli, McGill University Health Centre

    When at Third You Don't Succeed
    David L. Wyles, Denver Health and Hospital Authority

    'A' Case To Remember: Hepatitis A - Managing an Old Virus in New Populations at Risk
    Darcy Wooten, University of California San Diego

    Hepatocellular Carcinoma
    Susanna Naggie, Duke University

    Nonalcoholic Steatohepatitis
    Kathleen E. Corey, Massachusetts General Hospital
5:00 PM - 7:00 PM

Opening Session

  • Bernard Fields Lecture: The Ancient And Modern Origins Of HIV
    Michael Emerman, Fred Hutchinson Cancer Research Center

  • N’Galy-Mann Lecture: Translating HIV Science Into Population Impact: A Reality Check From the Frontline
    Alex Godwin Coutinho, Partners in Health in Rwanda
  • Performance by the Boston Children's Chorus

7:00 PM - 9:00 PMWelcome Reception

Monday, March 9, 2020

7:15 AM - 8:15 AMNetworking Session for New Investigators
8:30 AM - 9:30 AM

Plenary Lectures

  • HIV Cure From Bench to Bedside
    Sharon R. Lewin, University of Melbourne
     
  • Universal Test and Treat (UTT): Lessons From the Past and For the Future
    Kevin M. De Cock, Centers for Disease Control and Prevention
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Understanding and Preventing HIV Replication
    Moderators: Gilda Tachedjian, Burnet Institute, and Louis M. Mansky, University of Minnesota

  • Novel Assessments of Central Nervous System Pathogenesis
    Moderators: Jaime H. Vera Rojas, Brighton and Sussex Medical School, and Sara Gianella, University of California San Diego

  • Therapeutic Interventions for HIV Treatment and Eradication
    Moderators: María J. Buzón, Vall d'Hebrón Research Institute, and Aadia Rana, University of Alabama at Birmingham

  • Community- and Clinical-based HIV Treatment, Prevention Interventions, and Insights
    Moderators: LaRon E. Nelson, Yale University, and Wame Jallow, International Treatment Preparedness Coalition
12:00 PM - 1:30 PMLunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Sharpening the Cutting Edge: Additions to the Molecular Virology Toolkit
    Leader: Alan N. Engelman, Dana-Farber Cancer Institute

  • Hearts and Hormones
    Leader: Markella V. Zanni, Massachusetts General Hospital

  • Chronic Diseases in Maternal Health: Persistent Problems for Pregnant or Postpartum Women
    Leader: Risa M. Hoffman, University of California Los Angeles

  • Rapid ART Start: Where Are the Gaps?
    Leader: Izukanji Sikazwe, Centre for Infectious Disease Research in Zambia

  • Partner Notification for Detecting HIV Infections
    Leader: Rachel Baggaley, World Health Organization
2:30 PM - 4:00 PMPoster Abstract Sessions
4:00 PM - 6:00 PM

Concurrent Symposia

  • Novel Cure Interventions
    Conveners: Michaela Müller-Trutwin, Institute Pasteur, and Katharine J. Bar, University of Pennsylvania

    In Vivo Models For the Evaluation of Novel HIV Cure Interventions
    J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill

    LRA 2.0: Immune-Based Latency Reversal
    Ann Chahroudi, Emory University

    T-Cell and Hematopoietic Stem Cell Gene Therapies For HIV Cure
    Christopher Peterson, Fred Hutchinson Cancer Research Center

    Toward Durable Control of HIV-1 With eCD4-Ig
    Michael Farzan, The Scripps Research Institute
     
  • History Repeating Itself: Sexually Transmitted Infections in Women and Infants
    Convener: Karin Nielsen-Saines, University of California Los Angeles, and Victor Musiime, Makerere University

    Syphilis Causes Stillbirth: Penicillin is Prevention
    Melanie Taylor, World Health Organization

    Chlamydia and Gonorrhea in Pregnancy: Silence of the Germs
    Nicola Low, University of Bern

    Mother-to-Child Transmission of Hepatitis B: Can It Be Eliminated?
    Yusuke Shimakawa, Pasteur Institute

    Beyond The Stigma: A Sorely Needed Perspective on HSV
    Anna Wald, University of Washington
     
  • What Makes Epidemics Recede?
    Conveners: Victoria L. Mobley, North Carolina Department of Health and Human Services, and Maria Prins, Public Health Service of Amsterdam

    Reflections on the UK Epidemic
    Valerie Delpech, Public Health England

    30-Plus Years of HIV in Rakai: The Epidemic Recedes
    Joseph Kagaayi, Makerere University

    Battling HIV in the US Rural South
    Leandro Antonio Mena, University of Mississippi Medical Center

    How Do We Stop the Band From Playing On in the US?
    Carlos del Rio, Emory University

Tuesday, March 10, 2020

7:15 AM - 8:15 AM Networking Session for New Investigators
8:30 AM - 9:30 AM

Plenary Lectures

  • Preventing HIV Among People Who Inject Drugs: Plus ça Change, Plus ça Même Chose
    Steffanie A. Strathdee, University of California San Diego
     
  • Sex Differences in HIV
    Eileen P. Scully, Johns Hopkins University
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • HIV-Associated Malignancies and Tumor Viruses: An Expanding Landscape
    Moderators: Elizabeth A. Stier, Boston University, and Ronald T. Mitsuyasu, University of California Los Angeles

  • Targeting the Persistent HIV Reservoir
    Moderators: Guinevere Q. Lee, Weill Cornell Medical College, and Afam Okoye, Oregon Health and Science University

  • Cardiometabolic and Pulmonary Complications
    Moderators: Matthew J. Feinstein, Northwestern University, and Susanne Dam Nielsen, University of Copenhagen

  • Prevention 2020: Agents, Options, and Outcomes
    Moderators: Kenneth K. Mugwanya, Northwestern University, and Lisa Hirschhorn, Northwestern University
12:10 PM - 1:20 PM (Approximate)

Special Session

  • Special Lunch-Time Session on COVID-19
    This session will present state-of-the-art of what is known about the 2019-novel coronavirus (COVID-19) outbreak and its causative pathogen, 2019-nCoV. It will focus on the epidemiology and efforts in China; the global epidemiology and effort to control the outbreak; the virology of coronaviruses overall, molecular aspects of transmission to humans, and pathogenesis in mice models and parallels in humans; and the NIAID/NIH efforts to study novel coronaviruses and develop diagnostics, therapeutics, and vaccines.

    Speakers:
    Zunyou Wu, Chinese Center for Disease Control and Prevention
    15-minute live video update from China

    John T. Brooks, US Centers for Disease Control
    15-minute update

    Ralph S. Baric, University of North Carolina
    25-minute lecture

    Anthony S. Fauci, National Institute of Allergy and Infectious Diseases, National Institutes of Health
    15-minute recorded update for CROI attendees

    This session is in development. More information will be release once it becomes available.
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Curative Strategies: Trials and Tribulations
    Leader: Pablo Tebas, University of Pennsylvania

  • Alternative Diagnostic Tools for Understanding NeuroHIV
    Leader: Avindra Nath, National Institutes of Health

  • Fat in Focus
    Leader: Jacqueline Capeau, Sorbonne University

  • Novel Approaches to Study Pediatric Antiretroviral Dosing and Safety
    Leader: Adrie Bekker, Stellenbosch University

  • Coming Into the Light: HIV in Transgender Women and Men
    Leader: Sari L. Reisner, Harvard T.H. Chan School of Public Health, and Jan Anton Charles Hontelez, Erasmus University Medical Center
2:30 PM - 4:00 PM Poster Abstract Sessions
4:00 PM - 6:00 PM

Concurrent Symposia

  • Halt, Who Goes There? Virus Sensing and Restriction
    Conveners: Theodora Hatziioannou, The Rockefeller University, and Jeremy Luban, University of Massachusetts Medical School

    Sting in The Tail: How DNA Triggers Immune Responses to Viral Infections?
    Zhijian Chen, UT Southwestern Medical Center

    Trim5 Recognition And Restriction Of HIV-1 And Retroviruses
    Owen Pornillos, University of Virginia

    HIV-1 Avoids Being Zapped
    Janet L. Smith, University of Michigan

    SERINC Structure and Restriction of HIV-1 Infectivity
    Valerie Pye, The Francis Crick Institute
     
  • HIV is On Our Minds
    Conveners: Scott L. Letendre, University of California San Diego, and Matthias Cavassini, University of Lausanne

    NeuroHIV In The Global Context: Advancing the Continuum of Care and Achieving Equity
    Kiran T. Thakur, Columbia University

    HIV-Associated Neurocognitive Disorders and Aging in the Global Setting
    John Joska, University of Cape Town

    HIV and Mental Health: The Impact of the Comorbidity in Resource-Constrained Settings
    Bibilola D. Oladeji, University of Ibadan

    Cerebrovascular Disease and HIV in the Global Setting
    Felicia C. Chow, University of California San Francisco
     
  • B Cured
    Conveners: Annie F. Luetkemeyer, University of California San Francisco, and Arthur Kim, Harvard Medical School

    Global Elimination of Hepatitis B Virus
    Gilles Wandeler, Bern University Hospital

    Adapting the Immune Response to Cure Hepatitis B
    Barbara Rehermann, National Institutes of Health

    Hepatitis B Virus: New Agents
    Raymond T. Chung, Massachusetts General Hospital

    The Mathematics of Hepatitis B Cure
    Alan S. Perelson, Los Alamos National Laboratory
  • Contraception and HIV
    Conveners: James Kiarie,World Health Organization, and Yvette Raphael, Advocacy for Prevention of HIV and AIDS

    Drug-Drug Interactions: The Ups and Downs of Antiretroviral Plus Contraceptives
    Kimberly K. Scarsi, University of Nebraska Medical Center

    Contraceptive Implant Rollout in South Africa
    Gregory PetroUniversity of Cape Town

    Contraception and HIV Risk: A Conundrum No More
    Renee Heffron, University of Washington

    The State of SRHR & HIV Services For CIS-Gender Women: A Community Perpective
    Wame Jallow, International Treatment Preparedness Coalition
6:10 PM - 6:45 PM

Special Session

  • Late-Breaking News: Update From the HVTN 702 Vaccine (UHAMBO) Trial
    Moderator: Susan P. Buchbinder, San Francisco Department of Public Health

    Introduction of HVTN 702 Study
    Lawrence Corey, Fred Hutchinson Cancer Research Center

    Presentation of HVTN 702 Study Data
    Glenda E. Gray, University of the Witwatersrand

    Panelists: Lawrence Corey, Fred Hutchinson Cancer Research Center, Glenda E. Gray, University of the Witwatersrand, and Steven F. Wakefield, Fred Hutchinson Cancer Research Center

Wednesday, March 11, 2020

7:15 AM - 8:15 AM Networking Session for New Investigators
8:30 AM - 9:30 AM

Plenary Lectures

  • Recent Advances in the Diagnosis, Treatment, and Prevention of Tuberculosis
    Gavin Churchyard, Aurum Institute
     
  • Engineering Vaccine Immunity
    Shane Crotty, La Jolla Institute for Immunology
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Immunology and Pathogenesis of Lentivirus Infections
    Moderators: Zaza Ndhlovu, African Health Research Institute, and Sandhya Vasan, US ilitary HIV Research Program

  • Gone But Not Forgotten: HCV After Direct-Acting Antiviral Therapy
    Moderators: Vincent Lo Re, University of Pennsylvania, and Naglaa H. Shoukry, Université de Montréal

  • Critical Issues in Maternal and Child Health
    Moderators: Lisa Lynn Abuogi, University of Colorado Denver, and Paula Vaz, Fundação Ariel Glaser Contra o Sida Pediatrico

  • Tuberculosis, Opportunistic Infections, and HIV Testing
    Moderators: Joshua A. Barocas, Boston Medical Center, and Jose M. Miro, University of Barcelona

  • The Good, the Bad, and the Ugly: HIV Incidence and Outcomes in Selected Populations
    Moderators: Andrew Mujugira, Makerere University, and Kate Buchacz, Centers for Disease Control and Prevention
12:00 PM - 1:30 PM Lunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Attack of the Clones: Clonal Expansion in the HIV Reservoir
    Leader: Linos Vandekerckhove, Ghent University

  • The Long and the Short of It: What's Next for Long-Acting Drugs
    Leader: Ethel D. Weld, Johns Hopkins University

  • New Diagnostic Algorithms for Tuberculosis and Opportunistic Infections
    Leader: Andrew D. Kerkhoff, University of California San Francisco

  • Making Sense of It All: HIV Susceptibility in the Female Genital Tract
    Leader: Caroline Mitchell, Massachusetts General Hospital
2:30 PM - 4:00 PM Poster Abstract Sessions
4:00 PM - 6:00 PM

Concurrent Symposia

  • Double-Edged Sword of Inflammation
    Conveners: Douglas Kwon, Harvard Medical School, and Giulia Carla Marchetti, University of Milan

    Using Systems Biology to Understand The Mechanisms of Vaccine Efficacy
    Bali Pulendran, Stanford University

    Decoding the Transcriptional Inflammatory CASCADES That Maintain HIV Reservoir
    Susan Pereira Ribeiro, Case Western Reserve University

    Dissecting the Drivers of Chronic Inflammation
    Krystelle Nganou, University Hospital Erlangen

    Defining Treatable Pathways in Inflammaging: Is It Nice to Fool With Mother Nature?
    Michael M. Lederman, Case Western Reserve University
     
  • Antiretroviral Therapy: The Long Game
    Conveners: Nagalingeswaran Kumarasamy, Voluntary Health Services-Infectious Diseases Medical Centre, and Angela Colbers, Radbound University Medical Center

    Novel Antiretroviral Agents: Transforming The Care of People With HIV
    Rajesh T. Gandhi, Massachusetts General Hospital

    Pediatric and Adolescent ART: A Road Less Travelled
    Carolyn Bolton Moore, University of Alabama at Birmingham

    Metabolic Complications of HIV and Its Therapies
    Jordan E. Lake, University of Texas Health Science Center

    Getting It Right: Practical Approaches to Adherence With Modern ARVs
    Jose R. Castillo-Mancilla, University of Colorado Denver
     
  • Hepatitis C: Parallels, Pitfalls, and Promise
    Conveners: Risha Irvin, Johns Hopkins University, and Marina Klein, McGill University Health Centre Research Institute
    Global Epidemiology of Hepatitis C
    Yvan J-F Hutin, World Health Organization

    Modeling and Examples of HCV Elimination: Possibilities, Achievements, and Next Steps
    Natasha Martin, University of California San Diego

    Vertical Hepatitis C Transmission: Déjà Vu All Over Again?
    Ali Judd, University College London

    Hepatitis C Treatment on a Shoestring
    Isabelle Andrieux-Meyer, Drugs for Neglected Diseases Initiative