Boston, Massachusetts
March 8–11, 2020


Preliminary Agenda

The CROI Program and Information Guide, including all sessions and presentations, will be posted on the CROI website 1 week prior to the start of the conference.

Sunday, March 8, 2020

9:00 AM - 1:30 PM

  • Program Committee Workshop for New Investigators and Trainees
    Conveners: John W. Mellors, University of Pittsburgh, and Serena S. Spudich, Yale University

  • Martin Delaney Presentation: Shifting From Acute to Chronic: Aging, Longevity, and Lived Experience

2:00 PM - 4:00 PM

Concurrent Preconference Workshops

  • Frontiers in Laboratory Science
    Conveners: Galit Alter, Ragon Institute of MGH, MIT and Harvard, and Frank Kirchhoff, Ulm University Medical Center

    Shaping Vaccines With DNA Origami
    Mark Bathe, Massachusetts Institute of Technology

    Dead or Alive: Reservoir Landscape Analysis
    Janet Siliciano, Johns Hopkins University

    Charting Genome-Wide Integration
    Mary F. Kearney, NIH

    Mapping the Single Cell Epigenome by EpiTOF
    Alex J. Kuo, Stanford University
  • Clinical Trial Design and Analysis
    Conveners: Susan P. Buchbinder, San Francisco Department of Public Health, and Richard E. Chaisson, Johns Hopkins University

    Putting Analysis Into Analytical Treatment Interruptions
    Lu Zheng, Harvard T. H. Chan School of Public Health

    From 2 to 3: Phase 2C Trials
    Patrick Phillips, University of California San Francisco

    Non-Inferiority Complex
    Jeffrey Murray, Food and Drug Administration
  • Interactive Case-Based Workshop: What's Eating Your Liver
    Conveners: Oluwaseun Falade-Nwulia, Johns Hopkins University, and Nadine Kronfli, McGill University Health Centre

    When at Third You Don't Succeed
    David L. Wyles, Denver Health and Hospital Authority

    Hepatitis A, Hepatitis C, and End-Stage Liver Disease
    Darcy Wooten, University of California San Diego

    Hepatocellular Carcinoma
    Susanna Naggie, Duke University

    Nonalcoholic Steatohepatitis
    Kathleen E. Corey, Massachusetts General Hospital

5:00 PM - 7:00 PM

Opening Session

  • Bernard Fields Lecture
    Michael Emerman, Fred Hutchinson Cancer Research Center

  • N’Galy-Mann Lecture
    Alex Coutinho, Partners in Health in Rwanda

7:00 PM - 9:00 PM

Opening Reception

Monday, March 9, 2020

8:30 AM - 9:30 AM

Plenary Lectures

  • HIV Cure From Bench to Bedside
    Sharon R. Lewin, University of Melbourne
  • Trials and Tribulations of Test and Treat
    Kevin M. De Cock, CDC
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Understanding and Preventing HIV Replication
    Moderators: Kate Bishop, The Francis Crick Institute, and Gilda Tachedjian, Burnet Institute

  • Novel Assessments of Central Nervous System Pathogenesis
    Moderators: Tricia H. Burdo, Temple University, and Jaime Vera Rojas, Brighton and Sussex Medical School

  • Therapeutic Interventions for HIV Treatment and Eradication
    Moderators: María Buzón, Vall d'Hebrón Research Institute, and Aadia Rana, University of Alabama at Birmingham

  • Community- and Clinical-based HIV Treatment, Prevention Interventions, and Insights
    Moderators: LaRon E. Nelson, Yale University, and Wame Jallow, International Treatment Preparedness Coalition
12:00 PM - 1:30 PM Lunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Sharpening the Cutting Edge: Additions to the Molecular Virology Toolkit
    Leader: Alan N. Engelman, Harvard Medical School

  • Hearts and Hormones
    Leader: Markella V. Zanni, Massachusetts General Hospital

  • Chronic Diseases in Maternal Health: Persistent Problems for Pregnant or Postpartum Women
    Leader: Risa M. Hoffman, University of California Los Angeles

  • Rapid ART Start: Where Are the Gaps?
    Leader: Izukanji Sikazwe, Centre for Infectious Disease Research in Zambia

  • Partner Notification for Detecting HIV Infections
    Leader: Rachel Baggaley, WHO
2:30 PM - 4:00 PM Poster Abstract Sessions

4:00 PM - 6:00 PM

Concurrent Symposia

  • Novel Cure Interventions
    Conveners: Michaela Müller-Trutwin, Institute Pasteur, and Marina Caskey, The Rockefeller University

    Of Mice and Monkeys: Synergy of Models
    J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill

    LRA 2.0: Immune-Based Latency Reversal
    Ann Chahroudi, Emory University School of Medicine

    Hematopoietic Stem Cells and Gene Therapy
    Christopher Peterson, Fred Hutchinson Cancer Research Center

    eCD4lg as Efezarine Agent
    Michael Farzan, The Scripps Research Institute
  • History Repeating Itself: Sexually Transmitted Infections in Women and Infants
    Convener: Karin Nielsen-Saines, University of California Los Angeles

    Syphilis: The Grand Old Spirochete
    Melanie Taylor, World Health Organization

    Chlamydia and Gonorrhea: Young People's Diseases
    Nicola Low, University of Bern

    Hepatitis B: Can It Be Eliminated in Pregnancy or Before?
    Yusuke Shimakawa, Pasteur Institute

    Herpes Simplex Virus: Blistering On...
    Anna Wald, University of Washington
  • What Makes Epidemics Recede?
    Conveners: Victoria Mobley, North Carolina Department of Health and Human Services, and Maria Prins, Public Health Service Amsterdam

    Reflections on the UK Epidemic
    Valerie Delpech, Public Health England

    The Rakai Experience
    Joseph Kagaayi, Rakai Health Science Program

    Battling HIV in the US Rural South
    Leandro Antonio Mena, University of Mississippi Medical Center

    How Do We Stop the Band From Playing On in the US?
    Carlos del Rio, Emory University

Tuesday, March 10, 2020

8:00 AM - 9:30 AM

Plenary Lectures

  • Grappling With the Resurgence of Opioids and HIV
    Steffanie Strathdee, University of California San Diego
  • Sex Differences in HIV
    Eileen Scully, Johns Hopkins University School of Medicine
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • HIV-Associated Malignancies and Tumor Viruses: An Expanding Landscape
    Moderators: Elizabeth A. Stier, Boston University, and Denise Whitby, Frederick National Laboratory for Cancer Research

  • Targeting the Persistent HIV Reservoir
    Moderators: Guinevere Q. Lee, Weill Cornell Medicine, and Afam Okoye, Oregon Health and Science University

  • Cardiometabolic and Pulmonary Complications
    Moderators: Matthew J. Feinstein, Northwestern University, and Suzanne Dam Nielsen, Rigshospitalet

  • Prevention 2020: Agents, Options, and Outcomes
    Moderators: Suwat Chariyalertsak, Chiang Mai University, and Lisa Hirschhorn, Northwestern University
12:00 PM - 1:30 PM Lunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Curative Strategies: Trials and Tribulations
    Leader: Pablo Tebas, University of Pennsylvania

  • Alternative Diagnostic Tools for Understanding NeuroHIV
    Leader: Avindra Nath, NIH

  • Fat in Focus
    Leader: Jacqueline Capeau, Pierre and Marie Curie University

  • Novel Approaches to Study Pediatric Antiretroviral Dosing and Safety
    Leader: Adrie Bekker, Stellenbosch University

  • Coming Into the Light: HIV in Transgender Women and Men
    Leader: Jae Sevelius, University of California San Francisco
2:30 PM - 4:00 PM Poster Abstract Sessions

4:00 PM

Concurrent Symposia

  • Halt, Who Goes There? Virus Sensing and Restriction
    Conveners: Theodora, Hatziioannou, The Rockefeller University, and Jeremy Luban, University of Massachusetts Medical School

    Trim5alpha Recognition and Restriction of HIV-1 Capsid
    Owen Pornillos, University of Virginia

    Recognition of Viral DNA by Human Cgas and Expansion of the CGas/Sting System
    Zhijian Chen, University of Texas Southwestern Medical Center

    Structure of ZAP in Complex With RNA
    Janet Smith, University of Michigan

    SERINC Structure
    Valerie Pye, The Francis Crick Institute
  • HIV is On Our Minds

    Overview of Global NeuroHIV
    Kiran Thakur, Columbia University

    HIV-Associated Neurocognitive Disorders and Aging in the Global Setting
    John Joska, University of Cape Town

    HIV and Mental Health in the Global Setting
    Bibilola D. Oladeji, University of Ibadan

    Cerebrovascular Complications and NeuroHIV in the Global Setting
    Felicia C. Chow, University of California San Francisco
  • B Cured
    Conveners: Annie F. Luetkemeyer, University of California San Francisco, and Arthur Kim, Harvard Medical School

    Global Elimination of Hepatitis B Virus
    Gilles Wandeler, University of Bern

    Adapting the Immune Response to Cure Hepatitis B
    Barbara Rehermann, NIH

    Novel Pharmacology Strategies to Cure Hepatitis B
    Raymond T. Chung, Massachusetts General Hospital

    The Mathematics of Hepatitis B Cure
    Alan Perelson, Los Alamos National Laboratory
  • Contraception and HIV
    Conveners: James Kiarie, University of Washington, and Yvette Raphael, Advocacy for Prevention of HIV and AIDS

    Drug-Drug Interactions
    Kimberly K. Scarsi, University of Nebraska

    The Story of Implants in South Africa
    Gregory PetroUniversity of Cape Town

    Untangling Contraception and HIV Risk
    Renee Heffron, University of Washington

    HIV, Contraception, and Women's Choice: A Community Perspective
    Wame Mosime, International Treatment Preparedness Coalition

Wednesday, March 11, 2020

8:30 AM - 9:30 AM

Plenary Lectures

  • Tuberculosis: State of the Art
    Gavin Churchyard, The Aurum Institute
  • Engineering Vaccine Immunity
    Shane Crotty, La Jolla Institute for Allergy and Immunology
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Immunology and Pathogenesis of Lentivirus Infections
    Moderators: Zaza Ndhlovu, African Health Research Institute, and Sandhya Vasan, US Military HIV Research Program

  • Gone But Not Forgotten: HCV After Direct-acting Antiviral Therapy
    Moderators: Vincent Lo Re, University of Pennsylvania, and Naglaa Shoukry, Université de Montréal

  • Critical Issues in Maternal and Child Health
    Moderators: Lisa Abuogi, University of Colorado Denver, and Paula Vaz, Fundação Ariel Glaser Contra o Sida Pediatrico

  • Tuberculosis, Opportunistic Infections, and HIV Testing
    Moderators: Caryn Upton, Stellenbosch University, and James Ayieko, Kenya Medical Research Institute

  • The Good, the Bad, and the Ugly: HIV Incidence and Outcomes in Selected Populations
    Moderators: Andrew Mujugira, Makerere University, and Kate Buchacz, CDC
12:00 PM - 1:30 PM Lunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • The Road to a Better Vaccine: Clinical Trials and Cohort Studies
    Leader: Nicole Doria-Rose, NIH

  • Attack of the Clones: Clonal Expansion in the HIV Reservoir
    Leader: Linos Vandekerckhove, Ghent University

  • The Long and the Short of It: What's Next for Long-acting Drugs
    Leader: Ethel D. Weld, Johns Hopkins University

  • New Diagnostic Algorithms for Tuberculosis and Opportunistic Infections
    Leader: Susan E. Dorman, Medical University of South Carolina

  • Making Sense of It All: HIV Susceptibility in the Female Genital Tract
    Leader: Caroline Mitchell, Massachusetts General Hospital
2:30 PM - 4:00 PM Poster Abstract Sessions

4:00 PM - 6:00 PM

Concurrent Symposia

  • Double-Edged Sword of Inflammation
    Conveners: Jo-Ann Passmore, University of Cape Town, and Douglas Kwon, Harvard Medical School

    Controlling Inflammation to Program Vaccine Immunity
    Bali Pulendran, Emory University

    Decoding the Transcriptional Inflammatory CASCADES that Seed the Reservoir
    Susan Pereira Ribeiro, Case Western Reserve University

    Dissecting the Drivers of Chronic Inflammation
    Krystelle Nganou, NIH

    Whack-A-Mole: Defining Drugable Pathways in Inflamm-aging
    Michael M. Lederman, Case Western Reserve University
  • Antiretroviral Therapy: The Long Game
    Conveners: Nagalingeswaran Kumarasamy, Infectious Diseases Medical Centre, and Angela Colbers, Radbound University Medical Center

    Novel Mechanisms, New Agents, and How to Use Them
    Rajesh T. Gandhi, Massachusetts General Hospital and Ragon Institute

    ART From Start to Finish
    Carolyn Bolton Moore, University of Alabama at Birmingham

    Metabolic Complications of HIV and Its Therapies
    Jordan E. Lake, University of Texas Health Science Center

    Getting It Right: Practical Approaches to Adherence With Modern ARVs
    Jose R. Castillo-Mancilla, University of Colorado
  • Hepatitis C: Parallels, Pitfalls, and Promise

    Global Epidemiology of Hepatitis C
    Yvan Hutin, World Health Organization

    Modeling and Examples of Hepatitis C Elimination
    Natasha Martin, University of California San Diego

    Perinatal Hepatitis C Transmission: Déjà Vu All Over Again
    Ali Judd, University of College London

    Hepatitis C Treatment on a Shoestring
    Isabelle Andrieux-Meyer, Drugs for Neglected Diseases Initiative