CROI 2024 Preliminary Program

New Investigator Workshop

Scott M. Hammer Workshop for New Investigators and Trainees 

Widely considered the most informative and comprehensive session, this workshop highlights key presentations that will take place during CROI. Although the workshop is directed toward new investigators and trainees (eg, undergraduate students, graduate students, postdoctoral fellows, and physician fellows), all CROI attendees are encouraged to attend. Scholarship recipients are required to attend.

Moderators: Katharine J. Bar, Hospital of the University of Pennsylvania (Philadelphia, PA, USA), and Serena S. Spudich, Yale University (New Haven, CT, USA)

• • Community Perspective on CROI 2024
    Adam Castillejo, London Patient (London, United Kingdom)
  • Navigating Presentations in Molecular Virology at CROI 2024
    Frank Kirchhoff, Ulm University Medical Center (Ulm, Germany)
  • Navigating Presentations in SARS-CoV-2 and HIV Immunology
    Elizabeth Connick, University of Arizona (Tucson, AZ, USA)
  • Navigating Presentations in HIV Cure at CROI 2024
    Afam A. Okoye, Oregon Health and Sciences University (Portland, OR, USA)
  • Navigating Presentations in Prevention at CROI 2024
    LaRon Nelson, Yale University (New Haven, CT, USA)
  • Navigating Presentations in Pediatric HIV at CROI 2024
    Jennifer Jao, Northwestern University (Chicago, IL, USA)
  • Special Presentation by the Director of the NIAID
    Jeanne Marrazzo, National Institute of Allergy and Infectious Diseases (Bethesda, MD, USA)

CONCURRENT TECHNICAL WORKSHOPS

Opening Session

Bernard Fields Lecture

Barney Graham, NIAID Vaccine Research Center (Bethesda, Maryland, USA)

The Bernard Fields Lecture recognizes a basic scientist for important and relevant contributions to the fields of virology and viral pathogenesis.

N’Galy-Mann Lecture

Dorothy M’bori-Ngacha, Formerly with United Nations Children’s Fund (Nairobi, Kenya)

The N’Galy-Mann Lecture recognizes an HIV/AIDS researcher for important and relevant work in the fields of epidemiology or clinical research.

Martin Delaney

Frank Mugisha, Sexual Minorities Uganda (SMUG) (Kampala, Uganda)

The Martin Delaney Presentation recognizes the important work of community advocacy and engagement in research.

MONDAY PLENARY SESSION

What’s New in HIV Vaccines: Vaccine-Induced Immune Responses
Juliana M. McElrath, Fred Hutchinson Cancer Center (Seattle, WA, USA)

Shall We Reach HPV Elimination in the Face of Inequity?
Nelly Mugo, Kenya Medical Research Institute (Nairobi, Kenya)

CONCURRENT ORAL ABSTRACT SESSIONS

Oral Abstract Sessions include leading-edge research in HIV, hepatitis viruses, SARS-CoV-2, and other viral infections and their related conditions. During these 2-hour sessions, speakers present their peer-reviewed research on a specific topic area and respond to questions from attendees in 1 of 2 question and answer periods moderated by experts in the field.

• HIV Immunology and Vaccines
• Neuropathogenesis of HIV
• Clinical Trials of Novel Antiretroviral Therapies
• Game Changers in Prevention of HIV and Sexually Transmitted Infections

Lunch Break for Attendees and New Investigator Networking Sessions

CONCURRENT THEMED DISCUSSIONS

Themed Discussions include up to 5 select poster abstracts connected by a theme. A discussant provides a 5-minute introduction outlining the state of the topic field, and then each presenter gives a brief overview of their Poster Abstract in 5 minutes using 5 slides (recommended) to summarize the noteworthy results, conclusions, and discussion points. Discussants interact with audience members and presenters to create a discussion that synthesizes the relevant information, covers key points of agreement and controversy, and draws comparisons to related work in the scientific field. At the conclusion of a Themed Discussion, the discussant provides a 5-minute summation highlighting the key information of the Poster Abstracts discussed and posing important questions for future research.

• Viral Rebound
• Is the Weight Over: GLP-1 Agonists Are Here
• PEP Prevention Toolbox: Do We Know How to Use It?
• Hazards Ahead: The Intersection of HIV and Substance Use

POSTER SESSIONS

Poster Abstract Sessions comprise the majority of scientific information presented at CROI. Presenters of Poster Abstracts who attend CROI in person will be assigned to stand at their respective boards, organized by topic, on one of the 3 conference days. All posters will be available for viewing throughout the conference in the poster hall and in an electronic format on the CROI website and other electronic means (access is restricted to registered CROI attendees during the conference).

CONCURRENT INTERACTIVE SESSIONS AND SYMPOSIA

The HIV Vaccine Journey: Don’t Stop Believin’  

Moderators: Georgia D. Tomaras, Duke University (Durham, NC, USA), and Leonidas Stamatatos, Fred Hutchison Cancer Center (Seattle, WA, USA)

• Neutralizing Antibody Protection: Where Do We Go From Here?
  Yunda Huang, Fred Hutchison Cancer Center (Seattle, WA, USA)
• Germline Targeting Strategies to Get On the Road Again
  Rogier W. Sanders, Academic Medical Center (Amsterdam, Netherlands)
  
• Novel Immunization Strategies to Move on Down the Road
  Darrell Irvine, Massachusetts Institute of Technology (Cambridge, MA, USA)

Living Into Young Adulthood with Perinatal HIV

Moderator: Allison Agwu, Johns Hopkins University (Baltimore, MD, USA)

• Epidemiology of Perinatally Acquired HIV Among Adolescents and Young Adults
  Mutsawashe Bwakura-Dangarembizi, University of Zimbabwe (Harare, Zimbabwe)
• Social Determinants of Health Among Adolescents and Young Adults with Perinatal Acquire HIV
  Ezer Kang, Howard University (Washington, DC, USA)
• Cardiometabolic Risks and Complications: Adolescents and Young Adults with Perinatally Acquired HIV
  Sahera Dirajlal-Fargo, Ann & Robert H Lurie Children’s Hospital of Chicago (Chicago, IL, USA)

The Return of Syphilis

Moderators: Jodie Dionne, University of Alabama at Birmingham (Birmingham, AL, USA), and Alex de Voux, University of Cape Town (Cape Town, South Africa)

• Why Can’t We Do Better at Diagnosing Syphilis?
  Ina Park, University of California San Francisco (San Francisco, CA, USA)
• The Burgeoning Epidemic of Congenital Syphilis
  Angelica Espinosa Miranda, Ministry of Health (Brasilia, Brazil)
• Management Conundrums
  Khalil G. Ghanem, The Johns Hopkins University School of Medicine (Baltimore, MD, USA)

TUESDAY PLENARY SESSION

Resistance, HIV Assembly, and Maturation Inhibitors
Eric Freed, National Institutes of Health (Bethesda, MD, USA)

Short-Course Prevention and Treatment of Tuberculosis
Vidya Mave, Byramjee Jeejeebhoy Government Medical College (Pune, India)

CONCURRENT ORAL ABSTRACT SESSIONS

Oral Abstract Sessions include leading-edge research in HIV, hepatitis viruses, SARS-CoV-2, and other viral infections and their related conditions. During these 2-hour sessions, speakers present their peer-reviewed research on a specific topic area and respond to questions from attendees in 1 of 2 question and answer periods moderated by experts in the field.

• COVID-19: Epidemiologic and Clinical Insights
• Virus at the Wheel: Regulation of Replication and Immunity
• Combating Complications of HIV
• Hepatitis and Tuberculosis
• Leaning Into the Success of Biomedical HIV Prevention

Lunch Break for Attendees and New Investigator Networking Sessions

CONCURRENT THEMED DISCUSSIONS

Themed Discussions include up to 5 select poster abstracts connected by a theme. A discussant provides a 5-minute introduction outlining the state of the topic field, and then each presenter gives a brief overview of their Poster Abstract in 5 minutes using 5 slides (recommended) to summarize the noteworthy results, conclusions, and discussion points. Discussants interact with audience members and presenters to create a discussion that synthesizes the relevant information, covers key points of agreement and controversy, and draws comparisons to related work in the scientific field. At the conclusion of a Themed Discussion, the discussant provides a 5-minute summation highlighting the key information of the Poster Abstracts discussed and posing important questions for future research.

• Persistent Immune Activation and Inflammation During Antiretroviral Therapy
• Hypertension and HIV: Pregnancy, Postpartum, and Beyond
• Anal Cancer Screening and Pathogenesis
• Violence, Displacement, and HIV

POSTER SESSIONS

Poster Abstract Sessions comprise the majority of scientific information presented at CROI. Presenters of Poster Abstracts who attend CROI in person will be assigned to stand at their respective boards, organized by topic, on one of the 3 conference days. All posters will be available for viewing throughout the conference in the poster hall and in an electronic format on the CROI website and other electronic means (access is restricted to registered CROI attendees during the conference).

CONCURRENT INTERACTIVE SESSIONS AND SYMPOSIA

Not Just a Pretty Shape: HIV Assembly to Disassembly   

Moderators: Owen Pornillos, University of Virginia (Charlottesville, VA, USA), and Melissa Kane, University of Pittsburgh (Pittsburgh, PA, USA)

• Virion Assembly: Selecting the Right RNA
  Wei-Shau Hu, National Cancer Institute (Frederick, MD, USA)
• Virion Maturation: Folding Into the Right Shape
  Mamuka Kvaratskhelia, University of Colorado (Aurora, CO, USA)
• Virion Disassembly: Keeping it Together Until the Right Moment
  Gregory Towers, University College London (London, UK)

New Frontiers in Hepatitis B  

Moderators: Gilles Wandeler, University of Bern (Bern, Switzerland), and Gail Matthews, Kirby Institute (Sydney, Australia)

• Hepatitis B in Sub-Saharan Africa
  Olufunmilayo Lesi, World Health Organization (Geneva, Switzerland)
• Novel Markers of Hepatitis B
  Fabien Zoulim, L’Université Claude Bernard Lyon 1 (Lyon, France)
• Immunologic Control of Hepatitis B
  Adam Gehring, University of Toronto (Toronto, Canada)

Roundtable on DoxyPEP: Ready or Not…   

Moderators: Kenneth Ngure, Kenya Medical Research Institute (Nairobi, Kenya) and Michael Traeger, Monash University (Melbourne, Australia)

• Introduction: Understanding the Issues
  Chase Cannon, University of Washington (Seattle, WA, USA)
• Should We Worry About Antimicrobial Resistance?
  Béatrice Berçot, University Paris Cité (Paris, France)
• Implementation Issues
  Stephanie Cohen, San Francisco Department of Public Health (San Francisco, CA, USA)

Impact on HIV Care and Services Among Refugees, Displaced Persons, and Marginalized Populations 

Moderators: Wafaa El-Sadr, Columbia University (New York, NY, USA) and Carlos del Rio, Emory University (Atlanta, GA, USA)

• Overview of the Global Displacement Crisis
  Mesfin T. Tessema, International Rescue Committee (New York, NY, USA)
• Meeting the Needs of People Affected by HIV From Ukraine
  Milosz Parczewski, Pomeranian Medical University (Szczecin, Poland)
• Protracted Consequences of Displacement: A Perspective from the Syrian Crisis
  Fouad M. Fouad, American University of Beirut (Beirut, Lebanon)
• Lived Experience from Ukraine
  Yana Panfilova, Teenergizer (Kyiv, Ukraine)

WEDNESDAY PLENARY SESSION

The End of Oral? How Long-Acting Formulations Are Changing the Management of Infectious Diseases
Charles Flexner, The John Hopkins University (Baltimore, MD, USA)

New Frontiers in Testing: Technologies and Programs
Nitika Pai, McGill University (Montreal, Quebec, Canada)

CONCURRENT ORAL ABSTRACT SESSIONS

Oral Abstract Sessions include leading-edge research in HIV, hepatitis viruses, SARS-CoV-2, and other viral infections and their related conditions. During these 2-hour sessions, speakers present their peer-reviewed research on a specific topic area and respond to questions from attendees in 1 of 2 question and answer periods moderated by experts in the field.

• HIV Reservoir and Cure Strategies
• HIV Across the Life Continuum: Pregnant People, Infants, Children, and Adolescents
• HIV Epidemiology: Using Data to Inform Future Interventions
• Interventions to Improve HIV Testing and Treatment

Lunch Break for Attendees and New Investigator Networking Sessions

CONCURRENT THEMED DISCUSSIONS

Themed Discussions include up to 5 select poster abstracts connected by a theme. A discussant provides a 5-minute introduction outlining the state of the topic field, and then each presenter gives a brief overview of their Poster Abstract in 5 minutes using 5 slides (recommended) to summarize the noteworthy results, conclusions, and discussion points. Discussants interact with audience members and presenters to create a discussion that synthesizes the relevant information, covers key points of agreement and controversy, and draws comparisons to related work in the scientific field. At the conclusion of a Themed Discussion, the discussant provides a 5-minute summation highlighting the key information of the Poster Abstracts discussed and posing important questions for future research.

• Mucosal Immunity to HIV
• Strategies for an HIV Cure
• Dolutegravir Resistance in Resource-Limited Settings
• Novel Interventions in HIV Programming

POSTER SESSIONS

Poster Abstract Sessions comprise the majority of scientific information presented at CROI. Presenters of Poster Abstracts who attend CROI in person will be assigned to stand at their respective boards, organized by topic, on one of the 3 conference days. All posters will be available for viewing throughout the conference in the poster hall and in an electronic format on the CROI website and other electronic means (access is restricted to registered CROI attendees during the conference).

CONCURRENT INTERACTIVE SESSIONS AND SYMPOSIA

Innovations in Intervention: Toward an HIV Cure

Moderator: Marina Lusic, Heidelberg University (Heidelberg, Germany) and Maria Buzón, Vall d’Hebron Research Institute (Barcelona, Spain)

• From Mechanisms to Therapeutics: Eliminating Infected Cells by Inflammasome Activation
  Liang Shan, Washington University in St Louis (St Louis, MO, USA)
• From Therapeutics to Mechanisms: NNRTI Kills HIV-Infected Cells Through Inflammasome Activation
  Tracy L Diamond, Merck & Co, Inc (West Point, PA, USA)
• From Transcriptomics to Therapeutics: A Host Restriction Factor That Targets HIV Expression
  Rasmi Thomas, Walter Reed Army Institute of Research (Silver Spring, MD,USA)
• From Structure to Therapeutics: CD4 Mimetics Opens Env Conformation and Increases ADCC
  Andrés Finzi, Université de Montréal (Montreal, Canada)

Follow Your Heart: Managing Cardiovascular Disease Risk in PWH

Moderators: Matthew J Feinstein, Northwestern University (Chicago, IL, USA), and Franck Boccara (Sorbonne Universite, Paris, France)

• REPRIEVE Trial Overview: Mechanism Underlying Sex Differences in Assessing Risk of CVD
  Markella Zanni, Massachusetts General Hospital (Boston, MA, USA)
• What’s Next: Immune-Based Therapy for CVD and Comparison With the General Population
  Priscilla Y. Hsue, University of California San Francisco (San Francisco, CA, USA)
• Implications for Implementing CVD Risk Prevention Strategies for LMIC
  Mpiko Ntsekhe, University of Cape Town (Cape Town, South Africa)

Promise and Pitfalls of Biomedical Prevention: Beyond Phase III

Moderators: Linda-Gail Bekker, Desmond Tutu HIV Foundation (Cape Town, South Africa), and Bruno Spire, Institut National de la Santé et de la Recherche Médicale (Marseille, France)

• Why is Cabotegravir Rollout So Slow?
  Rupa Patel, Centers for Disease Control and Prevention (Atlanta, GA, USA)
• The Ring Comes Full Circle
  Leila E. Mansoor, Centre for the AIDS Programme of Research in South Africa (Durban, South Africa)
• Challenging the Dogma of Event-Driven PrEP
  Jenell Stewart, Hennepin Healthcare Research Institute (Minneapolis, MN, USA)