Search Abstracts

Background Accurately predicting the age and sex distribution of HIV over time is critical for precision interventions and resource planning. Progress towards epidemic control and changes in sexual partnership patterns over time impact this distribution. Characterizing age-specific sexual partner matrices may improve prediction accuracy and better inform programming for epidemic control. Methods We used data…

Background Transgender women (TGW) have an increased risk for HIV due to social exclusion, barriers to access to health care, discrimination, and exposure to higher-risk contexts such as sex work. In fact, there is a lack of studies assessing the dynamics of the HIV epidemic among TGW in rural cities. This is a cross-sectional study that…

Background Adolescents and young adults (AYA) 15-24 years represented more than a quarter of all new HIV infections globally in 2023. Data from two rounds of Population HIV Impact Assessments (PHIA) from four countries were used to estimate HIV incidence and assess progress in reducing incidence in AYA overall and by sex. Methods PHIAs are…

Background People living with perinatally acquired HIV (PPHIV) have unique circumstances: lifelong HIV and its associated inflammation, exposure to multiple suboptimal antiretroviral therapy regimens, HIV acquisition affecting early immune system development, and challenges in transitioning from pediatric to adult HIV care. They have higher rates of non-AIDS defining conditions and may potentially be at higher…

Background Advances in HIV care and treatment have substantially extended survival of people with HIV.  There is limited knowledge of the current health of the approximately 12,500 persons living with perinatally acquired HIV, i.e., Lifetime Survivors (LS), in the United States.  Methods We used data from the Medical Monitoring Project (MMP), a nationally representative sample of US…

Background HIV viral blips defined as a viral load between 51-999 copies/mL (preceded and followed by <50 cp/mL at least 1 to 12 months apart) occur among people with HIV (PWH) despite effective antiretroviral therapy (ART). Within the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD), we aimed to describe the prevalence and risk…

Background Racialized economic segregation significantly affects health outcomes by exacerbating disparities in disease prevalence and access to healthcare among marginalized communities. However, the impact of socioeconomic segregation on access to HIV pre-exposure prophylaxis (PrEP) across various socioeconomic groups remains unexplored in the US. Methods The Index of Concentration at the Extremes (ICE) quantifies segregation by…

Background HIV viral suppression is key to ending the HIV epidemic and maintaining the health of people with HIV (PWH). While prior research links substance use (SU) to lower antiretroviral therapy (ART) adherence, and higher HIV viral loads (VL) in PWH, newer ART regimes may be more resilient to intermittent adherence. We examined associations between…

Background Reducing HIV-related disparities is one of the four goals of the National HIV/AIDS Strategy. The Ending the HIV Epidemic (EHE) initiative, a key component of the Strategy, focuses on scaling up prevention and treatment services in priority jurisdictions. It is unclear what effect the EHE initiative may have on racial and ethnic health disparities…

Background Tracking changes over time in proportions and characteristics of persons living with HIV who are part of molecular clusters (clustering rates), has potential to provide valuable insights into HIV transmission dynamics and help guide targeted public health interventions for prevention. Methods We monitored clustering rates patterns and changes over time among key populations in…