Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.
CROI conference materials (eg, the conference program, Abstract eBook, electronic posters, CROI logo, etc) are protected by copyright. Permission to replicate or reproduce these elements, in whole or in part, must be obtained from the CROI Conference Manager, the International Antiviral Society-USA (IAS-USA). Study data (including figures within abstracts or electronic posters) are the property of the study authors. Permission to use data and figures cannot be given by IAS–USA unless it is for regulatory reasons. For more information, please email CROIabstracts@iasusa.org.
1277 Results
Background Understanding the prevalence and consequences of opportunistic infections (OIs) at antiretroviral therapy (ART) initiation remains critical for informing HIV testing and care strategies that reduce the likelihood of late presentation for care. We assessed trends in OIs at ART initiation and their association with 1-year survival in the North American AIDS Cohort Collaboration on…
Background Current TB diagnostics are suboptimal to detect TB in patients with advanced HIV disease (AHD) who are at high risk for disseminated TB and mortality. Blood has been overlooked as a compartment for TB diagnostics in AHD. We determined the diagnostic yield of routine screening for TB in blood using Xpert Ultra (UXpert) and Myco/F…
Background We have previously shown in cross-sectional studies that COVID-19 infection was associated with arterial stiffness and increased oxidized LDL (oxLDL). In this study, we assess changes in these cardiovascular parameters after COVID infection in a group of individuals who have documented pre-COVID assessments. Having pre-COVID assessments has been a limitation of current studies. Methods…
Background Long COVID (LC) is a newly defined syndrome linking COVID infection with an umbrella of long-lasting symptoms. Due to this variety of presentation and lack of understanding of the mechanism involved, no reliable biomarkers have been found so far, and diagnostic uncertainty remains high. In the prospect of personalized medicine, there is a dire…
Background Sepsis, often due to pneumonia, is a leading cause of death among people hospitalized in the US. HIV was a clear risk for death from pneumonia/sepsis in the pre-antiretroviral therapy (ART) era, but the impact of HIV in the current era is less clear. Sepsis mortality may be impacted by non-physiologic factors associated with…
Background Low serum cortisol has been associated with long COVID (LC) in some but not all studies. However, these studies examined untimed cortisol levels, which may not adequately assess adrenal function. Here we assessed untimed, timed, and stimulated cortisol levels and tested their association with LC. Methods Untimed total cortisol levels were quantified in 711…
Background Kidney transplantation (KT) between donors and recipients with HIV is promising. However, allograft rejection risk among recipients with HIV (R+) is higher than recipients without HIV (R-). This study evaluated predictive antibody markers of KT allograft rejection among R+. Methods The HOPE in Action Multicenter Kidney Trial performed KT in R+ between 2018-2021 from…
Background Prior studies have shown that persons aging with HIV are at higher risk for sarcopenia. Several consensus definitions have been developed for sarcopenia based upon combined muscle mass, performance and strength assessments. Because these approaches are not practical for routine clinical settings, the 5-item SARC-F questionnaire was validated to screen for sarcopenia in the…
Background Despite effective antiretroviral therapy (ART) and achieving virological suppression, a minority of adults living with HIV/AIDS (PLWHA) experience poor CD4+ T cell recovery, known as immune non-response (INR). The clinical outcomes for this population, particularly in relation to serious non-AIDS-related events (SNAE), remain poorly understood due to the challenges in controlling confounding factors across…
Background Lipohypertrophy (central adipose tissue (AT) accumulation) and AT abnormalities are common in people with HIV (PWH) and are key drivers of cardiometabolic co-morbidities. In a recent randomized, double-blind, placebo-controlled phase 2b clinical trial, we observed significant effects of the glucagon-like peptide-1 receptor agonist (GLP-1 RA), semaglutide, over 32 weeks on key outcome measures, including reductions…