Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.

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Search Results

1277 Results

1028 – HIV Exposure Does Not Affect Cytomegalovirus Acquisition Risk in a Setting of Optimized Maternal ART

Background Children who are HIV-exposed, uninfected (CHEU) have had higher incidence and earlier cytomegalovirus (CMV) acquisition than children who are HIV-unexposed, uninfected (CHUU), which may contribute to the higher morbidity and mortality observed among CHEU. To determine whether this difference in CMV acquisition persists in the era of optimized, universal ART, we assessed the probability,…

1024 – Obesity and Metabolic Comorbidities in Young Adults With Perinatal HIV Exposure Without Infection

Background The global scale-up of prenatal antiretroviral therapy (ART) has reduced the vertical transmission of HIV to <1%. In this context, a growing population of individuals with perinatal HIV exposure without infection (PHEU) has emerged, which now exceeds 20 million people worldwide. While growing evidence indicates that infants and children with PHEU are at increased…

1069 – Left Ventricular Mass Adjustment for Body Size in Youth With Perinatal HIV or Perinatal HIV Exposure

Background Cardiac-related complications were one of the most common causes of death in youth living with perinatally-acquired HIV (YPHIV) prior to widespread ART. However, diagnosing Left Ventricular Hypertrophy (LVH) typically relies on indices based on allometric exponents estimated from adults, which normalize Left Ventricular Mass (LVM) by body surface area (BSA) or height (HT) raised to…

1064 – Changes in Suicidality, Depression, and Anxiety After Integrative Mental Health Care in Thai Youth

Background This study aimed to assess suicidality, depression, and anxiety following the introduction of integrative mental health care into HIV services for Thai youth living with HIV (YLHIV). Methods A multicenter prospective cohort study was conducted among YLHIV (aged 15-24 years) and age and sex-matched HIV-negative youth in Thailand. Participants were assessed for suicidality, depression…

1056 – Prevalence and Consequences of Low-Level Viremia Among Adolescents Living With HIV in South Africa

Background Low-level viremia (LLV), defined by the World Health Organization as viral load between 51-999 copies/mL, has been shown to be associated with an increased risk of virological non-suppression and failure among adults on antiretroviral therapy (ART). It is unknown if adolescents living with HIV (ALHIV) and on ART, who are more likely to have…

986 – Depression, Sleep, and Anxiety Among Pregnant and Postpartum Women Using Dolutegravir and Efavirenz

Background Dolutegravir (DTG) and Efavirenz (EFV) have been associated with neuropsychiatric symptoms, which may impact adherence to antiretroviral therapy (ART) in pregnant and postpartum people living with HIV. However, their impact on postpartum mental health remains insufficiently understood. We compared depression, sleep disturbances and anxiety between DTG and EFV treatment in pregnant and postpartum people…

998 – Prematurity and Low Birth Weight in Children Born to Mothers Living With HIV in Spain

Background Children uninfected but exposed to HIV intra-utero (CHEU) are at higher risk of prematurity and low birth weight (LBW), factors associated with long-term growth impairment. Data is scarce regarding the effects of integrase inhibitor regimens during pregnancy in non-limited resource settings. Methods Descriptive retrospective study of mother-child pairs from 62 Spanish hospitals in the…

1031 – NK Cell KIR Education Is Associated With Low HIV DNA Load in Early ART-Treated Children

Background Early ART initiation, low immune activation, and effective anti-HIV NK cell responses have been linked with HIV remission in adults. It has been proposed that these features in combination with early life immunity may favour remission in children living with HIV (LWH). In a cohort of very early ART-treated children in KwaZulu-Natal, South Africa,…

1063 – Psychotic Disorders in Young Adults With Perinatally Acquired HIV: A Multicentre UK Study

Background Single cohort UK data suggests an increased lifetime prevalence of psychosis in young people living with perinatally acquired HIV (YPaHIV) compared to age matched peers in the general population (0.5-1.0%), echoed by US data. This is thought to be due to lifelong exposure to a neurotropic virus, neuroinflammation during brain development, and greater experience…

1075 – Early-Treated Children With Perinatal HIV Show Elevated Monocyte Activation Into Late Childhood

Background Early ART within 3 months of birth has dramatically improved long-term outcomes in children living with perinatal HIV. However, these children face decades of HIV-associated immune dysregulation and chronic inflammation. Neither the long-term inflammatory profile nor the risk of long-term non-communicable diseases are well understood. We assessed biomarkers associated with inflammation (monocyte and lymphocyte), metabolic and…