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1277 Results
Background The advent of antiretroviral treatment (ART) has led to an increase in the number of women living with HIV (HIV+) expressing interest in becoming pregnant. However, the availability of sexual and reproductive health services to support these women in their maternity plans is constrained in sub-Saharan Africa. This study examined intended and unintended pregnancies…
Background Sexually transmitted infections (STIs) during pregnancy are associated with adverse pregnancy outcomes. We evaluated the impact of diagnosing and treating curable STIs (Chlamydia [CT]/Gonorrhoea [NG]) during pregnancy on adverse pregnancy outcomes among women in a HIV pre-exposure prophylaxis (PrEP) cohort study in Cape Town, South Africa. Methods Eligible women >16 years, attending antenatal care, without…
Background With age, people with HIV (PWH) may face higher rates of physical comorbidities, psychosocial challenges and sexual health problems, all of which can impact quality of life and ART adherence. However, research on health among ageing PWH remains limited. This study aimed to examine self-reported physical, psychosocial and sexual health outcomes among people aged…
Background HIV infection is associated with an increased risk of human papillomavirus (HPV) acquisition, decreased clearance of HPV, and increased risk of precancerous lesions and cervical cancer. Despite the availability of antiretroviral therapy (ART), there is paucity of data describing the association between sustained HIV viral suppression and HPV infection. Achieving durable HIV viral suppression…
Background Kenyan guidelines recommend syndromic management for sexually transmitted infections (STIs) among people living with HIV at urogenital anatomical sites. However, STIs like Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) can cause morbidity and can be transmitted even without symptoms at multiple anatomical sites. We assessed the prevalence of CT and NG using universal nucleic…
Background Sexually transmitted infections (STIs) represent a major public health challenge, particularly as many cases are asymptomatic, complicating early detection, treatment, and partner notification, and contributing to ongoing transmission. This study aims to examine the role of asymptomatic STIs in a high-risk population of men who have sex with men (MSM), who regularly undergo STI…
Background In 2022 there were approximately 130,000 child HIV infections and 700,000 cases of congenital syphilis globally. Through concerted effort substantial progress has been made in both HIV and syphilis testing coverage to identify infections in pregnancy and to offer treatment. However, gaps remain, including the gap between HIV and syphilis testing. Dual HIV/syphilis rapid…
Background The US is experiencing an STI epidemic, with more than one-half of Americans at risk of an STI infection in their lifetime. An all-time high number of STIs was reported in 2021, with the combined number of cases for gonorrhea, syphilis, and chlamydia soaring to 2.54 million. To understand STI incidence among persons with…
Background Syphilis is associated with increased risk of HIV acquisition and poor pregnancy outcomes, including congenital syphilis. Syphilis remains a threat to public health despite accessible screening and treatment. This study examines the prevalence of syphilis among reproductive-age (18-45 years) women with or without HIV enrolled between 2021 and 2023 in the Study of Treatment…
Background Unmet need for family planning (FP) is used to measure gaps in FP access and use, and for women living with HIV (WLWH), risk of vertical HIV transmission. Criterion to assess need for FP are used in FP/HIV integrated services to direct FP service delivery, yet applying the World Health Organization (WHO) definition of…