Abstracts from 2014 through the most recent CROI can be viewed in this searchable database once they have been presented at the conference. Abstract Contents: The searchable database includes abstract text as submitted by the authors prior to CROI. Study data might be updated during the presentation at CROI. Please refer to the electronic poster or webcast for updates. Searching the Abstract Database: Enter the criteria below and click the “Search” button. After the search has been entered, the results will appear below the search form.
CROI conference materials (eg, the conference program, Abstract eBook, electronic posters, CROI logo, etc) are protected by copyright. Permission to replicate or reproduce these elements, in whole or in part, must be obtained from the CROI Conference Manager, the International Antiviral Society-USA (IAS-USA). Study data (including figures within abstracts or electronic posters) are the property of the study authors. Permission to use data and figures cannot be given by IAS–USA unless it is for regulatory reasons. For more information, please email CROIabstracts@iasusa.org.
1277 Results
Background The transition to integrase inhibitors has been associated with weight gain and increases in cardiometabolic risk factors, but evidence for the impact of this transition over longer time horizons in populations with HIV-negative comparators is limited. We evaluated the impact of the switch from efavirenz to dolutegravir (DTG) on weight and a suite of…
Background Digital health interventions are a promising approach for increasing access to health information and services, but low or non-sustained engagement can limit effectiveness. We examined how exposure to and engagement with a digital family planning and reproductive health (FP/RH) intervention (“CyberRwanda”) influenced the intervention’s impact for Rwandan adolescents. Methods A 3-arm, cluster randomized, hybrid…
Background The anticipated approval of lenacapavir for HIV pre-exposure prophylaxis (PrEP) may present an opportunity to better address inequitable PrEP implementation among priority populations in the United States (US). We examined potential preferences for long-acting PrEP methods among transgender and gender-diverse (TGD) adults in the US. Methods From April to June 2022, we conducted an…
Background In southern Africa the provision of pre-exposure prophylaxis (PrEP) has not translated into population-level impact due to the challenges of taking a daily oral pill. Injectable PrEP provides an opportunity to overcome this barrier. Using clinical process data from the Long-Acting PrEP Integrated with Sexual and Reproductive Health (LAPIS) trial, we explore changes in patterns…
Background PopART was a cluster randomized trial (CRT) designed to evaluate universal testing and treatment (UTT) strategies for HIV prevention. While CRTs are the gold standard for evaluating population-level effects, they can be subject to selection bias when those enrolled differ from the population of interest. PopART included two intervention arms: (A) combination prevention with…
Background Antiretroviral therapy (ART) improves clinical outcomes of people living with HIV (PLHIV) and achieving viral suppression through ART can prevent HIV transmission. We compared prevalence and correlates of unsuppressed viral load among PLHIV from two Tanzania HIV Impact Surveys (THISs). The first (survey 1 [S1]) was conducted from October 2016-August 2017; the second (survey…
Background Disengagement from antiretroviral treatment undermines HIV programme success. Current approaches targeting interventions at specific demographic groups miss most people out of care. Classifying patterns of engagement could use precision public health principles to identify unique care needs, and inform service development targeted at patients with similar experiences. Methods Using routine health data from the…
Background As cycling in and out of HIV care over time becomes the norm for people with HIV, most commencing antiretroviral therapy are now restarting rather than initiating treatment for the first time. Understanding patterns of engagement after a substantial treatment interruption could help to direct service implementation and choice of interventions for this crucial…
Background Long acting preexposure prophylaxis (PrEP) can address periods of partial adherence among individuals using oral PrEP. Using PrEP dispensing records, we determined the proportion of partially adherent men-who-have-sex-with-men (MSM) in Thailand who return within ten weeks and could benefit from cabotegravir as long-acting PrEP (CAB-LA). We then used a mathematical HIV transmission model to…
Background People who inject drugs (PWID) continue to experience high HIV incidence in a number of settings, including India; however, HIV is not homogeneously distributed in PWID and varies across social (injection partners) and spatial (injection venues) networks. To maximize impact of evidence-based interventions for PWID, it is critical to identify novel delivery points, including…