CONFERENCE ON RETROVIRUSES
AND OPPORTUNISTIC INFECTIONS

March 8–11, 2020

 

Virtual CROI 2020 Agenda

Please note: All times listed are in Eastern Daylight Time

Sunday, March 8, 2020

9:00 AM - 12:25 PM
  • Program Committee Workshop for New Investigators and Trainees
    Conveners: John W. Mellors, University of Pittsburgh, and Serena S. Spudich, Yale University

    Advances in Molecular Virology
    Wesley I. Sundquist, University of Utah

    Advances in HIV Immunology and Vaccines
    Richard A. Koup, National Institutes of Health

    Issues in Maternal, Infant, and Child Health
    Hermione Lyall, Imperial College Healthcare NHS Trust

    Advances in HIV Prevention
    Susan P. Buchbinder, San Francisco Department of Public Health

    Advances in HIV Cure
    Nicolas Chomont, Université de Montréal
2:00 PM - 4:00 PM

Concurrent Preconference Workshops

 
  • Frontiers in Laboratory Science
    Conveners: Galit Alter, Ragon Institute of MGH, MIT and Harvard, and John M. Coffin, Tufts University

    Shaping Vaccines With DNA Origami
    Mark Bathe, Massachusetts Institute of Technology

    Concepts In Reservoir Measurements
    Janet M. Siliciano, Johns Hopkins University

    Charting Genome-Wide Integration
    Mary F. Kearney, National Cancer Institute

    Single-Cell Epigenetics: Coloring Immune Cells With a Rich Pallette of Histone Marks
    Alex J. Kuo, Stanford University
     
  • Clinical Trial Design and Analysis
    Conveners: Susan P. Buchbinder, San Francisco Department of Public Health, and Richard E. Chaisson, Johns Hopkins University

    Putting Analysis Into Analytical Treatment Interruptions
    Lu Zheng, Harvard T. H. Chan School of Public Health

    Advancing From Phase II to Phase III: Navigating the Land of Expectations
    Patrick PJ Phillips, University of California San Francisco

    Noninferiority Complex
    Jeffrey Scott Murray, Food and Drug Administration

    Inclusion of Diverse Populations In Trials
    Mark Harrington, Treatment Action Group
     
  • Interactive Case-Based Workshop: What's Eating Your Liver
    Conveners: Jürgen K. Rockstroh, University of Bonn, and Robert T. Schooley, University of California San Diego

    When at Third You Don't Succeed
    David L. Wyles, Denver Health and Hospital Authority

    'A' Case To Remember: Hepatitis A - Managing an Old Virus in New Populations at Risk
    Darcy Wooten, University of California San Diego

    Hepatocellular Carcinoma
    Susanna Naggie, Duke University

    Nonalcoholic Steatohepatitis
    Kathleen E. Corey, Massachusetts General Hospital
5:00 PM - 7:00 PM

Opening Session

  • Bernard Fields Lecture: The Ancient And Modern Origins Of HIV
    Michael Emerman, Fred Hutchinson Cancer Research Center

  • N’Galy-Mann Lecture: Translating HIV Science Into Population Impact: A Reality Check From the Frontline
    Alex Godwin Coutinho, Partners in Health in Rwanda

Monday, March 9, 2020

8:30 AM - 9:30 AM

Plenary Lectures

  • HIV Cure From Bench to Bedside
    Sharon R. Lewin, University of Melbourne
     
  • Universal Test and Treat (UTT): Lessons From the Past and For the Future
    Kevin M. De Cock, Centers for Disease Control and Prevention
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Understanding and Preventing HIV Replication
    Moderators: John M. Coffin, Tufts University, and Richard A. Koup, National Institutes of Health
     
  • Novel Assessments of Central Nervous System Pathogenesis
    Moderators: Constance A. Benson, University of California San Diego, and Joseph J. Eron, University of North Carolina at Chapel Hill
     
  • Therapeutic Interventions for HIV Treatment and Eradication
    Moderators: Michael Saag, University of Alabama and Judith S. Currier, University of California Los Angeles
     
  • Community- and Clinical-based HIV Treatment, Prevention Interventions, and Insights
    Moderators: Wafaa M. El-Sadr, ICAP at Columbia University, and Richard E. Chaisson, Johns Hopkins University
12:00 PM - 1:30 PM Lunch Break
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Sharpening the Cutting Edge: Additions to the Molecular Virology Toolkit
    Leader: John M. Coffin, Tufts University
     
  • Hearts and Hormones
    Leader: Judith S. Currier, University of California Los Angeles
     
  • Chronic Diseases in Maternal Health: Persistent Problems for Pregnant or Postpartum Women
    Leader: Landon Myer, University of Cape Town
     
  • Rapid ART Start: Where Are the Gaps?
    Leader: Wafaa M. El-Sadr, ICAP at Columbia University
     
  • Partner Notification for Detecting HIV Infections
    Leader: Susan P. Buchbinder, San Francisco Department of Public Health
2:30 PM - 4:00 PM Poster Abstract Sessions (Please view all poster abstracts on the CROI Mobile App, including the electronic abstract posters)
4:00 PM - 6:00 PM

Concurrent Symposia

  • Novel Cure Interventions
    Conveners: Galit Alter, Ragon Institute of MGH, MIT and Harvard, and Richard A. Koup, National Institutes of Health

    In Vivo Models For the Evaluation of Novel HIV Cure Interventions
    J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill

    LRA 2.0: Immune-Based Latency Reversal
    Ann Chahroudi, Emory University

    T-Cell and Hematopoietic Stem Cell Gene Therapies For HIV Cure
    Christopher Peterson, Fred Hutchinson Cancer Research Center

    Toward Durable Control of HIV-1 With eCD4-Ig
    Michael Farzan, The Scripps Research Institute
     
  • History Repeating Itself: Sexually Transmitted Infections in Women and Infants
    Convener: Landon Myer, University of Cape Town , and Annette H. Sohn, Therapeutics Research, Education and AIDS Training Asia

    Syphilis Causes Stillbirth: Penicillin is Prevention
    Melanie Taylor, World Health Organization

    Chlamydia and Gonorrhea in Pregnancy: Silence of the Germs
    Nicola Low, University of Bern

    Mother-to-Child Transmission of Hepatitis B: Can It Be Eliminated?
    Yusuke Shimakawa, Pasteur Institute

    Beyond The Stigma: A Sorely Needed Perspective on HSV
    Anna Wald, University of Washington
     
  • What Makes Epidemics Recede?
    Conveners: Wafaa M. El-Sadr, ICAP at Columbia University, and Susan P. Buchbinder, San Francisco Department of Public Health

    Reflections on the UK Epidemic
    Valerie Delpech, Public Health England

    30-Plus Years of HIV in Rakai: The Epidemic Recedes
    Joseph Kagaayi, Makerere University

    Battling HIV in the US Rural South
    Leandro Antonio Mena, University of Mississippi Medical Center

    How Do We Stop the Band From Playing On in the US?
    Carlos del Rio, Emory University

Tuesday, March 10, 2020

8:30 AM - 9:30 AM

Plenary Lectures

  • Preventing HIV Among People Who Inject Drugs: Plus ça Change, Plus ça Même Chose
    Steffanie A. Strathdee, University of California San Diego
     
  • Sex Differences in HIV
    Eileen P. Scully, Johns Hopkins University
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • HIV-Associated Malignancies and Tumor Viruses: An Expanding Landscape
    Moderators: James A. Hoxie, University of Pennsylvania, and Constance A. Benson, University of California San Diego
     
  • Targeting the Persistent HIV Reservoir
    Moderators: Joseph J. Eron, University of North Carolina at Chapel Hill, and Richard A. Koup, National Institutes of Health
     
  • Cardiometabolic and Pulmonary Complications
    Moderators: Judith S. Currier, University of California Los Angeles, and Annette H. Sohn, Therapeutics Research, Education and AIDS Training Asia
     
  • Prevention 2020: Agents, Options, and Outcomes
    Moderators: Sharon L. Hillier, University of Pittsburgh, and Susan P. Buchbinder, San Francisco Department of Public Health
12:10 PM - 1:20 PM (Approximate)

Special Session

  • Special Lunch-Time Session on COVID-19
    This session will present state-of-the-art of what is known about the 2019-novel coronavirus (COVID-19) outbreak and its causative pathogen, SARS-CoV-2. It will focus on the epidemiology and efforts in China; the global epidemiology and effort to control the outbreak; the virology of coronaviruses overall, molecular aspects of transmission to humans, and pathogenesis in mice models and parallels in humans; and the NIAID/NIH efforts to study novel coronaviruses and develop diagnostics, therapeutics, and vaccines.

    Speakers:
    Zunyou Wu, Chinese Center for Disease Control and Prevention
    15-minute live video update from China

    John T. Brooks, US Centers for Disease Control and Prevention
    15-minute update

    Ralph S. Baric, University of North Carolina
    25-minute lecture

    Anthony S. Fauci, National Institute of Allergy and Infectious Diseases, National Institutes of Health
    15-minute recorded update for CROI attendees

    This session is in development. More information will be release once it becomes available.
1:30 PM - 2:30 PM

Concurrent Themed Discussions

  • Curative Strategies: Trials and Tribulations
    Leader: Joseph J. Eron, University of North Carolina at Chapel Hill
     
  • Alternative Diagnostic Tools for Understanding NeuroHIV
    Leader: Michael Saag, University of Alabama
     
  • Fat in Focus
    Leader: Judith S. Currier, University of California Los Angeles
     
  • Novel Approaches to Study Pediatric Antiretroviral Dosing and Safety
    Leader: Annette H. Sohn, Therapeutics Research, Education and AIDS Training Asia
     
  • Coming Into the Light: HIV in Transgender Women and Men
    Leader: Susan P. Buchbinder, San Francisco Department of Public Health
2:30 PM - 4:00 PM Poster Abstract Sessions (Please view all poster abstracts on the CROI Mobile App, including the electronic abstract posters)
4:00 PM - 6:00 PM

Concurrent Symposia

  • Halt, Who Goes There? Virus Sensing and Restriction
    Conveners: James A. Hoxie, University of Pennsylvania, and John M. Coffin, Tufts University

    Sting in The Tail: How DNA Triggers Immune Responses to Viral Infections?
    Zhijian Chen, UT Southwestern Medical Center

    Trim5 Recognition And Restriction Of HIV-1 And Retroviruses
    Owen Pornillos, University of Virginia

    HIV-1 Avoids Being Zapped
    Janet L. Smith, University of Michigan

    SERINC Structure and Restriction of HIV-1 Infectivity
    Valerie Pye, The Francis Crick Institute
     
  • HIV is On Our Minds
    Convener: Elaine J. Abrams, ICAP at Columbia University

    NeuroHIV In The Global Context: Advancing the Continuum of Care and Achieving Equity
    Kiran T. Thakur, Columbia University

    HIV-Associated Neurocognitive Disorders and Aging in the Global Setting
    John Joska, University of Cape Town

    HIV and Mental Health: The Impact of the Comorbidity in Resource-Constrained Settings
    Bibilola D. Oladeji, University of Ibadan

    Cerebrovascular Disease and HIV in the Global Setting
    Felicia C. Chow, University of California San Francisco
     
  • B Cured
    Conveners: Robert T. Schooley, University of California San Diego, and Annette H. Sohn, Therapeutics Research, Education and AIDS Training Asia

    Global Elimination of Hepatitis B Virus
    Gilles Wandeler, Bern University Hospital

    Adapting the Immune Response to Cure Hepatitis B
    Barbara Rehermann, National Institutes of Health

    Hepatitis B Virus: New Agents
    Raymond T. Chung, Massachusetts General Hospital

    The Mathematics of Hepatitis B Cure
    Alan S. Perelson, Los Alamos National Laboratory
  • Contraception and HIV
    Conveners: Sharon L. Hillier, University of Pittsburgh, and Landon Myer, University of Cape Town

    Drug-Drug Interactions: The Ups and Downs of Antiretroviral Plus Contraceptives
    Kimberly K. Scarsi, University of Nebraska Medical Center

    Contraceptive Implant Rollout in South Africa
    Gregory PetroUniversity of Cape Town

    Contraception and HIV Risk: A Conundrum No More
    Renee Heffron, University of Washington

    The State of SRHR & HIV Services For CIS-Gender Women: A Community Perpective
    Wame Jallow, International Treatment Preparedness Coalition

Wednesday, March 11, 2020

8:30 AM - 9:30 AM

Plenary Lectures

  • Recent Advances in the Diagnosis, Treatment, and Prevention of Tuberculosis
    Gavin Churchyard, Aurum Institute
     
  • Engineering Vaccine Immunity
    Shane Crotty, La Jolla Institute for Immunology
10:00 AM - 12:00 PM

Concurrent Oral Abstract Sessions

  • Immunology and Pathogenesis of Lentivirus Infections
    Moderators: Galit Alter, Ragon Institute of MGH, MIT and Harvard, James A. Hoxie, University of Pennsylvania, and Richard A. Koup, National Institutes of Health
     
  • Gone But Not Forgotten: HCV After Direct-Acting Antiviral Therapy
    Moderators: Michael Saag, University of Alabama, and Robert T. Schooley, University of California San Diego
     
  • Critical Issues in Maternal and Child Health
    Moderators: Elaine J. Abrams, ICAP at Columbia University, Landon Myer, University of Cape Town, and Annette H. Sohn, Therapeutics Research, Education and AIDS Training Asia
     
  • Tuberculosis, Opportunistic Infections, and HIV Testing
    Moderators: Constance A. Benson, University of California San Diego, and Richard E. Chaisson, Johns Hopkins University
     
  • The Good, the Bad, and the Ugly: HIV Incidence and Outcomes in Selected Populations
    Moderators: Wafaa M. El-Sadr, ICAP at Columbia University, and Susan P. Buchbinder, San Francisco Department of Public Health
12:00 PM - 12:30 PM Lunch Break
12:30 PM - 1:00 PM

Special Session

  • Late-Breaking News: Update From the HVTN 702 Vaccine (UHAMBO) Trial
    Moderator: Susan P. Buchbinder, San Francisco Department of Public Health

    Introduction of HVTN 702 Study
    Lawrence Corey, Fred Hutchinson Cancer Research Center

    Presentation of HVTN 702 Study Data
    Glenda E. Gray, University of the Witwatersrand

    Panelists: Lawrence Corey, Fred Hutchinson Cancer Research Center, Glenda E. Gray, University of the Witwatersrand, and Steven F. Wakefield, Fred Hutchinson Cancer Research Center
1:30 PM - 2:30 PM

Concurrent Themed Discussions


  • The Road to a Better Vaccine: Clinical Trials and Cohort Studies
    Leader: Richard A. Koup, National Institutes of Health
     
  • Attack of the Clones: Clonal Expansion in the HIV Reservoir
    Leader: John M. Coffin, Tufts University
     
  • The Long and the Short of It: What's Next for Long-Acting Drugs
    Leader: Judith S. Currier, University of California Los Angeles  
  • New Diagnostic Algorithms for Tuberculosis and Opportunistic Infections
    Leader: Constance A. Benson, University of California San Diego
     
  • Making Sense of It All: HIV Susceptibility in the Female Genital Tract
    Leader: Sharon L. Hillier, University of Pittsburgh
2:30 PM - 4:00 PM Poster Abstract Sessions (Please view all poster abstracts on the CROI Mobile App, including the electronic abstract posters)
4:00 PM - 6:00 PM

Concurrent Symposia

  • Double-Edged Sword of Inflammation
    Conveners: Galit Alter, Ragon Institute of MGH, MIT and Harvard, and James A. Hoxie, University of Pennsylvania

    Using Systems Biology to Understand The Mechanisms of Vaccine Efficacy
    Bali Pulendran, Stanford University

    Decoding the Transcriptional Inflammatory CASCADES That Maintain HIV Reservoir
    Susan Pereira Ribeiro, Case Western Reserve University

    Dissecting the Drivers of Chronic Inflammation
    Krystelle Nganou, University Hospital Erlangen

    Defining Treatable Pathways in Inflammaging: Is It Nice to Fool With Mother Nature?
    Michael M. Lederman, Case Western Reserve University
     
  • Antiretroviral Therapy: The Long Game
    Conveners: Michael Saag, University of Alabama and Elaine J. Abrams, ICAP at Columbia University

    Novel Antiretroviral Agents: Transforming The Care of People With HIV
    Rajesh T. Gandhi, Massachusetts General Hospital

    Pediatric and Adolescent ART: A Road Less Travelled
    Carolyn Bolton Moore, University of Alabama at Birmingham

    Metabolic Complications of HIV and Its Therapies
    Jordan E. Lake, University of Texas Health Science Center

    Getting It Right: Practical Approaches to Adherence With Modern ARVs
    Jose R. Castillo-Mancilla, University of Colorado Denver
     
  • Hepatitis C: Parallels, Pitfalls, and Promise
    Conveners: Wafaa M. El-Sadr, ICAP at Columbia University, and Sharon L. Hillier, University of Pittsburgh
    Global Epidemiology of Hepatitis C
    Yvan J-F Hutin, World Health Organization

    Modeling and Examples of HCV Elimination: Possibilities, Achievements, and Next Steps
    Natasha Martin, University of California San Diego

    Vertical Hepatitis C Transmission: Déjà Vu All Over Again?
    Ali Judd, University College London

    Hepatitis C Treatment on a Shoestring
    Isabelle Andrieux-Meyer, Drugs for Neglected Diseases Initiative